diff --git a/packages/react-devtools-shared/src/__tests__/utils-test.js b/packages/react-devtools-shared/src/__tests__/utils-test.js
index 9e781e072ba75..f35cacc73308f 100644
--- a/packages/react-devtools-shared/src/__tests__/utils-test.js
+++ b/packages/react-devtools-shared/src/__tests__/utils-test.js
@@ -26,6 +26,7 @@ import {
   REACT_STRICT_MODE_TYPE as StrictMode,
 } from 'shared/ReactSymbols';
 import {createElement} from 'react';
+import {symbolicateSource} from '../symbolicateSource';
 
 describe('utils', () => {
   describe('getDisplayName', () => {
@@ -385,6 +386,35 @@ describe('utils', () => {
     });
   });
 
+  describe('symbolicateSource', () => {
+    const source = `"use strict";
+Object.defineProperty(exports, "__esModule", { value: true });
+exports.f = f;
+function f() { }
+//# sourceMappingURL=`;
+    const result = {
+      column: 16,
+      line: 1,
+      sourceURL: 'http://test/a.mts',
+    };
+    const fs = {
+      'http://test/a.mts': `export function f() {}`,
+      'http://test/a.mjs.map': `{"version":3,"file":"a.mjs","sourceRoot":"","sources":["a.mts"],"names":[],"mappings":";;AAAA,cAAsB;AAAtB,SAAgB,CAAC,KAAI,CAAC"}`,
+      'http://test/a.mjs': `${source}a.mjs.map`,
+      'http://test/b.mjs': `${source}./a.mjs.map`,
+      'http://test/c.mjs': `${source}http://test/a.mjs.map`,
+      'http://test/d.mjs': `${source}/a.mjs.map`,
+    };
+    const fetchFileWithCaching = async (url: string) => fs[url] || null;
+    it('should parse source map urls', async () => {
+      const run = url => symbolicateSource(fetchFileWithCaching, url, 4, 10);
+      await expect(run('http://test/a.mjs')).resolves.toStrictEqual(result);
+      await expect(run('http://test/b.mjs')).resolves.toStrictEqual(result);
+      await expect(run('http://test/c.mjs')).resolves.toStrictEqual(result);
+      await expect(run('http://test/d.mjs')).resolves.toStrictEqual(result);
+    });
+  });
+
   describe('formatConsoleArguments', () => {
     it('works with empty arguments list', () => {
       expect(formatConsoleArguments(...[])).toEqual([]);
diff --git a/packages/react-devtools-shared/src/hooks/SourceMapConsumer.js b/packages/react-devtools-shared/src/hooks/SourceMapConsumer.js
index 779cbb3b2f0d1..8e6503685bdb5 100644
--- a/packages/react-devtools-shared/src/hooks/SourceMapConsumer.js
+++ b/packages/react-devtools-shared/src/hooks/SourceMapConsumer.js
@@ -24,8 +24,8 @@ type SearchPosition = {
 type ResultPosition = {
   column: number,
   line: number,
-  sourceContent: string,
-  sourceURL: string,
+  sourceContent: string | null,
+  sourceURL: string | null,
 };
 
 export type SourceMapConsumerType = {
@@ -118,18 +118,11 @@ function BasicSourceMapConsumer(sourceMapJSON: BasicSourceMap) {
     const line = nearestEntry[2] + 1;
     const column = nearestEntry[3];
 
-    if (sourceContent === null || sourceURL === null) {
-      // TODO maybe fall back to the runtime source instead of throwing?
-      throw Error(
-        `Could not find original source for line:${lineNumber} and column:${columnNumber}`,
-      );
-    }
-
     return {
       column,
       line,
-      sourceContent: ((sourceContent: any): string),
-      sourceURL: ((sourceURL: any): string),
+      sourceContent: ((sourceContent: any): string | null),
+      sourceURL: ((sourceURL: any): string | null),
     };
   }
 
diff --git a/packages/react-devtools-shared/src/hooks/parseHookNames/parseSourceAndMetadata.js b/packages/react-devtools-shared/src/hooks/parseHookNames/parseSourceAndMetadata.js
index 40bfed48ba53f..15423c12416cc 100644
--- a/packages/react-devtools-shared/src/hooks/parseHookNames/parseSourceAndMetadata.js
+++ b/packages/react-devtools-shared/src/hooks/parseHookNames/parseSourceAndMetadata.js
@@ -276,6 +276,11 @@ function parseSourceAST(
             columnNumber,
             lineNumber,
           });
+        if (sourceContent === null || sourceURL === null) {
+          throw Error(
+            `Could not find original source for line:${lineNumber} and column:${columnNumber}`,
+          );
+        }
 
         originalSourceColumnNumber = column;
         originalSourceLineNumber = line;
diff --git a/packages/react-devtools-shared/src/symbolicateSource.js b/packages/react-devtools-shared/src/symbolicateSource.js
index d28ed42e59db0..9430e88b3fc15 100644
--- a/packages/react-devtools-shared/src/symbolicateSource.js
+++ b/packages/react-devtools-shared/src/symbolicateSource.js
@@ -39,7 +39,7 @@ export async function symbolicateSourceWithCache(
 }
 
 const SOURCE_MAP_ANNOTATION_PREFIX = 'sourceMappingURL=';
-async function symbolicateSource(
+export async function symbolicateSource(
   fetchFileWithCaching: FetchFileWithCaching,
   sourceURL: string,
   lineNumber: number, // 1-based
@@ -63,11 +63,12 @@ async function symbolicateSource(
       const sourceMapAnnotationStartIndex = resourceLine.indexOf(
         SOURCE_MAP_ANNOTATION_PREFIX,
       );
-      const sourceMapURL = resourceLine.slice(
+      const sourceMapAt = resourceLine.slice(
         sourceMapAnnotationStartIndex + SOURCE_MAP_ANNOTATION_PREFIX.length,
         resourceLine.length,
       );
 
+      const sourceMapURL = new URL(sourceMapAt, sourceURL).toString();
       const sourceMap = await fetchFileWithCaching(sourceMapURL).catch(
         () => null,
       );
@@ -84,29 +85,33 @@ async function symbolicateSource(
             columnNumber, // 1-based
           });
 
+          if (possiblyURL === null) {
+            return null;
+          }
           try {
-            void new URL(possiblyURL); // This is a valid URL
+            // sourceMapURL = https://react.dev/script.js.map
+            void new URL(possiblyURL); // test if it is a valid URL
             const normalizedURL = normalizeUrl(possiblyURL);
 
             return {sourceURL: normalizedURL, line, column};
           } catch (e) {
             // This is not valid URL
-            if (possiblyURL.startsWith('/')) {
+            if (
+              // sourceMapURL = /file
+              possiblyURL.startsWith('/') ||
+              // sourceMapURL = C:\\...
+              possiblyURL.slice(1).startsWith(':\\\\')
+            ) {
               // This is an absolute path
               return {sourceURL: possiblyURL, line, column};
             }
 
             // This is a relative path
-            const [sourceMapAbsolutePathWithoutQueryParameters] =
-              sourceMapURL.split(/[?#&]/);
-
-            const absoluteSourcePath =
-              sourceMapAbsolutePathWithoutQueryParameters +
-              (sourceMapAbsolutePathWithoutQueryParameters.endsWith('/')
-                ? ''
-                : '/') +
-              possiblyURL;
-
+            // possiblyURL = x.js.map, sourceMapURL = https://react.dev/script.js.map
+            const absoluteSourcePath = new URL(
+              possiblyURL,
+              sourceMapURL,
+            ).toString();
             return {sourceURL: absoluteSourcePath, line, column};
           }
         } catch (e) {
diff --git a/packages/react-devtools-shared/src/utils.js b/packages/react-devtools-shared/src/utils.js
index 5b0903883c301..ffbc9e390d5a4 100644
--- a/packages/react-devtools-shared/src/utils.js
+++ b/packages/react-devtools-shared/src/utils.js
@@ -1017,7 +1017,7 @@ export function backendToFrontendSerializedElementMapper(
   };
 }
 
-// This is a hacky one to just support this exact case.
+// Chrome normalizes urls like webpack-internals:// but new URL don't, so cannot use new URL here.
 export function normalizeUrl(url: string): string {
   return url.replace('/./', '/');
 }