diff --git a/source/common/common/BUILD b/source/common/common/BUILD
index f5632b8fee27..bf7701a21fa8 100644
--- a/source/common/common/BUILD
+++ b/source/common/common/BUILD
@@ -320,6 +320,7 @@ envoy_cc_library(
     external_deps = ["abseil_synchronization"],
     deps = envoy_cc_platform_dep("thread_impl_lib") + [
         ":non_copyable",
+        "//source/common/singleton:threadsafe_singleton",
     ],
 )
 
diff --git a/source/common/common/thread.h b/source/common/common/thread.h
index 4808d391dfbd..8c9d991268aa 100644
--- a/source/common/common/thread.h
+++ b/source/common/common/thread.h
@@ -8,6 +8,7 @@
 #include "envoy/thread/thread.h"
 
 #include "common/common/non_copyable.h"
+#include "common/singleton/threadsafe_singleton.h"
 
 #include "absl/synchronization/mutex.h"
 
@@ -168,5 +169,19 @@ class AtomicPtr : private AtomicPtrArray<T, 1, alloc_mode> {
   T* get(const MakeObject& make_object) { return BaseClass::get(0, make_object); }
 };
 
+struct MainThread {
+  using MainThreadSingleton = InjectableSingleton<MainThread>;
+  bool inMainThread() const { return main_thread_id_ == std::this_thread::get_id(); }
+  static void init() { MainThreadSingleton::initialize(new MainThread()); }
+  static void clear() {
+    free(MainThreadSingleton::getExisting());
+    MainThreadSingleton::clear();
+  }
+  static bool isMainThread() { return MainThreadSingleton::get().inMainThread(); }
+
+private:
+  std::thread::id main_thread_id_{std::this_thread::get_id()};
+};
+
 } // namespace Thread
 } // namespace Envoy
diff --git a/source/common/thread_local/thread_local_impl.cc b/source/common/thread_local/thread_local_impl.cc
index 0815236a3195..9bf485419745 100644
--- a/source/common/thread_local/thread_local_impl.cc
+++ b/source/common/thread_local/thread_local_impl.cc
@@ -16,13 +16,14 @@ namespace ThreadLocal {
 thread_local InstanceImpl::ThreadLocalData InstanceImpl::thread_local_data_;
 
 InstanceImpl::~InstanceImpl() {
-  ASSERT(std::this_thread::get_id() == main_thread_id_);
+  ASSERT(Thread::MainThread::isMainThread());
   ASSERT(shutdown_);
   thread_local_data_.data_.clear();
+  Thread::MainThread::clear();
 }
 
 SlotPtr InstanceImpl::allocateSlot() {
-  ASSERT(std::this_thread::get_id() == main_thread_id_);
+  ASSERT(Thread::MainThread::isMainThread());
   ASSERT(!shutdown_);
 
   if (free_slot_indexes_.empty()) {
@@ -91,7 +92,7 @@ void InstanceImpl::SlotImpl::runOnAllThreads(const UpdateCb& cb) {
 }
 
 void InstanceImpl::SlotImpl::set(InitializeCb cb) {
-  ASSERT(std::this_thread::get_id() == parent_.main_thread_id_);
+  ASSERT(Thread::MainThread::isMainThread());
   ASSERT(!parent_.shutdown_);
 
   for (Event::Dispatcher& dispatcher : parent_.registered_threads_) {
@@ -105,7 +106,7 @@ void InstanceImpl::SlotImpl::set(InitializeCb cb) {
 }
 
 void InstanceImpl::registerThread(Event::Dispatcher& dispatcher, bool main_thread) {
-  ASSERT(std::this_thread::get_id() == main_thread_id_);
+  ASSERT(Thread::MainThread::isMainThread());
   ASSERT(!shutdown_);
 
   if (main_thread) {
@@ -119,7 +120,7 @@ void InstanceImpl::registerThread(Event::Dispatcher& dispatcher, bool main_threa
 }
 
 void InstanceImpl::removeSlot(uint32_t slot) {
-  ASSERT(std::this_thread::get_id() == main_thread_id_);
+  ASSERT(Thread::MainThread::isMainThread());
 
   // When shutting down, we do not post slot removals to other threads. This is because the other
   // threads have already shut down and the dispatcher is no longer alive. There is also no reason
@@ -146,7 +147,7 @@ void InstanceImpl::removeSlot(uint32_t slot) {
 }
 
 void InstanceImpl::runOnAllThreads(Event::PostCb cb) {
-  ASSERT(std::this_thread::get_id() == main_thread_id_);
+  ASSERT(Thread::MainThread::isMainThread());
   ASSERT(!shutdown_);
 
   for (Event::Dispatcher& dispatcher : registered_threads_) {
@@ -158,7 +159,7 @@ void InstanceImpl::runOnAllThreads(Event::PostCb cb) {
 }
 
 void InstanceImpl::runOnAllThreads(Event::PostCb cb, Event::PostCb all_threads_complete_cb) {
-  ASSERT(std::this_thread::get_id() == main_thread_id_);
+  ASSERT(Thread::MainThread::isMainThread());
   ASSERT(!shutdown_);
   // Handle main thread first so that when the last worker thread wins, we could just call the
   // all_threads_complete_cb method. Parallelism of main thread execution is being traded off
@@ -185,7 +186,7 @@ void InstanceImpl::setThreadLocal(uint32_t index, ThreadLocalObjectSharedPtr obj
 }
 
 void InstanceImpl::shutdownGlobalThreading() {
-  ASSERT(std::this_thread::get_id() == main_thread_id_);
+  ASSERT(Thread::MainThread::isMainThread());
   ASSERT(!shutdown_);
   shutdown_ = true;
 }
diff --git a/source/common/thread_local/thread_local_impl.h b/source/common/thread_local/thread_local_impl.h
index 7abed0499166..e098723d7232 100644
--- a/source/common/thread_local/thread_local_impl.h
+++ b/source/common/thread_local/thread_local_impl.h
@@ -19,7 +19,7 @@ namespace ThreadLocal {
  */
 class InstanceImpl : Logger::Loggable<Logger::Id::main>, public NonCopyable, public Instance {
 public:
-  InstanceImpl() : main_thread_id_(std::this_thread::get_id()) {}
+  InstanceImpl() { Thread::MainThread::init(); }
   ~InstanceImpl() override;
 
   // ThreadLocal::Instance
@@ -81,7 +81,6 @@ class InstanceImpl : Logger::Loggable<Logger::Id::main>, public NonCopyable, pub
   // A list of index of freed slots.
   std::list<uint32_t> free_slot_indexes_;
   std::list<std::reference_wrapper<Event::Dispatcher>> registered_threads_;
-  std::thread::id main_thread_id_;
   Event::Dispatcher* main_thread_dispatcher_{};
   std::atomic<bool> shutdown_{};
 
diff --git a/source/server/server.cc b/source/server/server.cc
index 1d5f95378f28..26795a8b2aed 100644
--- a/source/server/server.cc
+++ b/source/server/server.cc
@@ -89,7 +89,7 @@ InstanceImpl::InstanceImpl(
                                                   : nullptr),
       grpc_context_(store.symbolTable()), http_context_(store.symbolTable()),
       router_context_(store.symbolTable()), process_context_(std::move(process_context)),
-      main_thread_id_(std::this_thread::get_id()), hooks_(hooks), server_contexts_(*this) {
+      hooks_(hooks), server_contexts_(*this) {
   try {
     if (!options.logPath().empty()) {
       try {
@@ -819,7 +819,7 @@ InstanceImpl::registerCallback(Stage stage, StageCallbackWithCompletion callback
 }
 
 void InstanceImpl::notifyCallbacksForStage(Stage stage, Event::PostCb completion_cb) {
-  ASSERT(std::this_thread::get_id() == main_thread_id_);
+  ASSERT(Thread::MainThread::isMainThread());
   const auto it = stage_callbacks_.find(stage);
   if (it != stage_callbacks_.end()) {
     for (const StageCallback& callback : it->second) {
diff --git a/source/server/server.h b/source/server/server.h
index 117107524827..cf4d24eadd56 100644
--- a/source/server/server.h
+++ b/source/server/server.h
@@ -362,7 +362,6 @@ class InstanceImpl final : Logger::Loggable<Logger::Id::main>,
   Router::ContextImpl router_context_;
   std::unique_ptr<ProcessContext> process_context_;
   std::unique_ptr<Memory::HeapShrinker> heap_shrinker_;
-  const std::thread::id main_thread_id_;
   // initialization_time is a histogram for tracking the initialization time across hot restarts
   // whenever we have support for histogram merge across hot restarts.
   Stats::TimespanPtr initialization_timer_;
diff --git a/test/common/thread_local/thread_local_impl_test.cc b/test/common/thread_local/thread_local_impl_test.cc
index 59bdd6d0080b..de6c67318c6a 100644
--- a/test/common/thread_local/thread_local_impl_test.cc
+++ b/test/common/thread_local/thread_local_impl_test.cc
@@ -15,6 +15,26 @@ using testing::ReturnPointee;
 namespace Envoy {
 namespace ThreadLocal {
 
+TEST(MainThreadVerificationTest, All) {
+  // Main thread singleton is initialized in the constructor of tls instance. Call to main thread
+  // verification will fail before that.
+  EXPECT_DEATH(Thread::MainThread::isMainThread(),
+               "InjectableSingleton used prior to initialization");
+  {
+    EXPECT_DEATH(Thread::MainThread::isMainThread(),
+                 "InjectableSingleton used prior to initialization");
+    InstanceImpl tls;
+    // Call to main thread verification should succeed after tls instance has been initialized.
+    ASSERT(Thread::MainThread::isMainThread());
+    tls.shutdownGlobalThreading();
+    tls.shutdownThread();
+  }
+  // Main thread singleton is cleared in the destructor of tls instance. Call to main thread
+  // verification will fail after that.
+  EXPECT_DEATH(Thread::MainThread::isMainThread(),
+               "InjectableSingleton used prior to initialization");
+}
+
 class TestThreadLocalObject : public ThreadLocalObject {
 public:
   ~TestThreadLocalObject() override { onDestroy(); }