diff --git a/nodeenv.py b/nodeenv.py
index 0ed0d67..6ddb021 100755
--- a/nodeenv.py
+++ b/nodeenv.py
@@ -55,7 +55,7 @@
 
 is_PY3 = sys.version_info[0] >= 3
 is_WIN = platform.system() == 'Windows'
-is_CYGWIN = platform.system().startswith('CYGWIN')
+is_CYGWIN = platform.system().startswith(('CYGWIN', 'MSYS'))
 
 ignore_ssl_certs = False