-
Notifications
You must be signed in to change notification settings - Fork 1
/
IKNaThCx.mod
executable file
·49 lines (40 loc) · 952 Bytes
/
IKNaThCx.mod
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
TITLE Na+-activated K+ current I_K[Na] in cortical and NRT cells
COMMENT
The model equations are the same as in [1].
References:
[1] Bischoff, U., Vogel, W., and Safranov, B.V.Na+-activated K+
channels in small dorsal root ganglion neurones of rat. Journal of
Physiology, 510.3: 743—754, 1998.
Written by Martynas Dervinis @Cardiff University, 2017.
ENDCOMMENT
NEURON {
SUFFIX iknaThCx
USEION k READ ek WRITE ik
USEION na READ nai
RANGE ek, gkbar, w_inf, nai_half, q10
}
UNITS {
(molar) = (1/liter)
(mM) = (millimolar)
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
gkbar = 0.00133 (mho/cm2)
ek = -90 (mV)
nai = 10 (mM)
nai_half = 38.7 (mM)
nai_exp = 3.5
}
ASSIGNED {
v (mV)
celsius (degC)
ik (mA/cm2)
w_inf
q10
}
BREAKPOINT {
q10 = 2.3^((celsius - 37) / 10)
w_inf = 1/(1 + (nai_half/nai)^nai_exp)
ik = q10 * gkbar * w_inf * (v - ek)
}