diff --git a/conan/tools/meson/meson.py b/conan/tools/meson/meson.py
index 4827ea3ec41..2d7317b80f0 100644
--- a/conan/tools/meson/meson.py
+++ b/conan/tools/meson/meson.py
@@ -47,7 +47,7 @@ def configure(self, reconfigure=False):
         cmd += "".join([f'{cmd_param} "{meson_option}"' for meson_option in meson_filenames])
         cmd += ' "{}" "{}"'.format(build_folder, source_folder)
         if self._conanfile.package_folder:
-            cmd += ' -Dprefix="{}"'.format(self._conanfile.package_folder)
+            cmd += ' -Dprefix="{}"'.format(self._conanfile.package_folder.replace("\\", "/"))
         if reconfigure:
             cmd += ' --reconfigure'
         self._conanfile.output.info("Meson configure cmd: {}".format(cmd))
diff --git a/conan/tools/meson/toolchain.py b/conan/tools/meson/toolchain.py
index e9b77d8e4ba..d4cec0da483 100644
--- a/conan/tools/meson/toolchain.py
+++ b/conan/tools/meson/toolchain.py
@@ -32,11 +32,6 @@ class MesonToolchain(object):
     [constants]
     preprocessor_definitions = [{% for it, value in preprocessor_definitions.items() -%}
     '-D{{ it }}="{{ value}}"'{%- if not loop.last %}, {% endif %}{% endfor %}]
-    # Constants to be overridden by conan_meson_deps_flags.ini (if exists)
-    deps_c_args = []
-    deps_c_link_args = []
-    deps_cpp_args = []
-    deps_cpp_link_args = []
 
     [project options]
     {% for it, value in project_options.items() -%}
@@ -69,16 +64,16 @@ class MesonToolchain(object):
     {% if backend %}backend = '{{backend}}' {% endif %}
     {% if pkg_config_path %}pkg_config_path = '{{pkg_config_path}}'{% endif %}
     # C/C++ arguments
-    c_args = {{c_args}} + preprocessor_definitions + deps_c_args
-    c_link_args = {{c_link_args}} + deps_c_link_args
-    cpp_args = {{cpp_args}} + preprocessor_definitions + deps_cpp_args
-    cpp_link_args = {{cpp_link_args}} + deps_cpp_link_args
+    c_args = {{c_args}} + preprocessor_definitions
+    c_link_args = {{c_link_args}}
+    cpp_args = {{cpp_args}} + preprocessor_definitions
+    cpp_link_args = {{cpp_link_args}}
     {% if is_apple_system %}
     # Objective-C/C++ arguments
-    objc_args = {{objc_args}} + preprocessor_definitions + deps_c_args
-    objc_link_args = {{objc_link_args}} + deps_c_link_args
-    objcpp_args = {{objcpp_args}} + preprocessor_definitions + deps_cpp_args
-    objcpp_link_args = {{objcpp_link_args}} + deps_cpp_link_args
+    objc_args = {{objc_args}} + preprocessor_definitions
+    objc_link_args = {{objc_link_args}}
+    objcpp_args = {{objcpp_args}} + preprocessor_definitions
+    objcpp_link_args = {{objcpp_link_args}}
     {% endif %}
 
     {% for context, values in cross_build.items() %}
diff --git a/conans/test/functional/toolchains/meson/test_meson.py b/conans/test/functional/toolchains/meson/test_meson.py
index 3a846b87e35..52c9cf02fc1 100644
--- a/conans/test/functional/toolchains/meson/test_meson.py
+++ b/conans/test/functional/toolchains/meson/test_meson.py
@@ -235,3 +235,64 @@ def build(self):
     # Checking the order of the appended user file (the order matters)
     match = re.search(r"meson setup --native-file .* --native-file \"myfilename\.ini\"", client.out)
     assert match
+
+
+@pytest.mark.tool("meson")
+@pytest.mark.skipif(platform.system() != "Windows", reason="Only for Windows")
+@pytest.mark.skipif(sys.version_info.minor < 8, reason="Latest Meson versions needs Python >= 3.8")
+def test_meson_using_prefix_path_in_application():
+    """
+    Issue related https://github.com/conan-io/conan/issues/14213
+    """
+    meson_build = textwrap.dedent("""
+    project('myhello ', 'c')
+    executable('myhello', 'src/main.c', install: true)
+
+    prefix_dir = get_option('prefix')
+    cfg_var = configuration_data()
+    cfg_var.set_quoted('MYHELLO_PREFIX', prefix_dir)
+
+    config_file = configure_file(
+        configuration: cfg_var,
+        output: 'config.h'
+    )
+    """)
+    main_c = textwrap.dedent("""
+    #include <config.h>
+
+    int main(void) {
+        return 0;
+    }
+
+    char *issue_func() {
+        return (MYHELLO_PREFIX);
+    }
+    """)
+    conanfile = textwrap.dedent("""
+    from conan import ConanFile
+    from conan.tools.meson import Meson
+    from conan.tools.layout import basic_layout
+
+    class myhelloConan(ConanFile):
+        name = "demo"
+        version = "0.1"
+        settings = "os", "compiler", "build_type", "arch"
+        exports_sources = "meson.build", "*.c"
+        package_type = "application"
+        generators = "MesonToolchain"
+
+        def layout(self):
+            basic_layout(self)
+
+        def build(self):
+            meson = Meson(self)
+            meson.configure()
+            meson.build()
+    """)
+    client = TestClient()
+    client.save({"conanfile.py": conanfile,
+                 "src/main.c": main_c,
+                 "meson.build": meson_build})
+    client.run("build .")
+    assert "unrecognized character escape sequence" not in str(client.out)  # if Visual
+    assert "unknown escape sequence" not in str(client.out)  # if mingw