diff --git a/Configuration/AlCa/python/autoAlca.py b/Configuration/AlCa/python/autoAlca.py
index ab1eec7399b72..51f166826ffe7 100644
--- a/Configuration/AlCa/python/autoAlca.py
+++ b/Configuration/AlCa/python/autoAlca.py
@@ -124,3 +124,11 @@ def buildList(pdList, matrix):
              'allForPromptCosmics'  : buildList(['Cosmics'], AlCaRecoMatrix),
              'allForExpressCosmics' : buildList(['ExpressCosmics'], AlCaRecoMatrix) }
 autoAlca.update(AlCaRecoMatrix)
+
+# list of AlCa sequences that have modules that do not support concurrent LuminosityBlocks
+AlCaNoConcurrentLumis = [
+    'PromptCalibProd',                 # AlcaBeamSpotProducer
+    'PromptCalibProdSiPixelAli',       # AlignmentProducerAsAnalyzer, MillePedeFileConverter
+    'PromptCalibProdBeamSpotHP',       # AlcaBeamSpotProducer
+    'PromptCalibProdBeamSpotHPLowPU',  # AlcaBeamSpotProducer
+]
diff --git a/Configuration/Applications/python/ConfigBuilder.py b/Configuration/Applications/python/ConfigBuilder.py
index ab050086b91ab..f87fe67ec4ce7 100644
--- a/Configuration/Applications/python/ConfigBuilder.py
+++ b/Configuration/Applications/python/ConfigBuilder.py
@@ -1275,7 +1275,7 @@ def prepare_ALCA(self, sequence = None, workflow = 'full'):
         # decide which ALCA paths to use
         alcaList = sequence.split("+")
         maxLevel=0
-        from Configuration.AlCa.autoAlca import autoAlca
+        from Configuration.AlCa.autoAlca import autoAlca, AlCaNoConcurrentLumis
         # support @X from autoAlca.py, and recursion support: i.e T0:@Mu+@EG+...
         self.expandMapping(alcaList,autoAlca)
         self.AlCaPaths=[]
@@ -1283,6 +1283,10 @@ def prepare_ALCA(self, sequence = None, workflow = 'full'):
             alcastream = getattr(alcaConfig,name)
             shortName = name.replace('ALCARECOStream','')
             if shortName in alcaList and isinstance(alcastream,cms.FilteredStream):
+                if shortName in AlCaNoConcurrentLumis:
+                    print("Setting numberOfConcurrentLuminosityBlocks=1 because of AlCa sequence {}".format(shortName))
+                    self._options.nConcurrentLumis = "1"
+                    self._options.nConcurrentIOVs = "1"
                 output = self.addExtraStream(name,alcastream, workflow = workflow)
                 self.executeAndRemember('process.ALCARECOEventContent.outputCommands.extend(process.OutALCARECO'+shortName+'_noDrop.outputCommands)')
                 self.AlCaPaths.append(shortName)