diff --git a/Configuration/StandardSequences/python/VtxSmeared.py b/Configuration/StandardSequences/python/VtxSmeared.py
index 8961f2e148839..fb7e2ae99f0e2 100644
--- a/Configuration/StandardSequences/python/VtxSmeared.py
+++ b/Configuration/StandardSequences/python/VtxSmeared.py
@@ -66,6 +66,7 @@
     'Run3FlatOpticsGaussSigmaZ4p2cm'     : 'IOMC.EventVertexGenerators.VtxSmearedRun3FlatOpticsGaussSigmaZ4p2cm_cfi',
     'Run3FlatOpticsGaussSigmaZ5p3cm'     : 'IOMC.EventVertexGenerators.VtxSmearedRun3FlatOpticsGaussSigmaZ5p3cm_cfi',
     'Realistic25ns900GeV2021Collision' : 'IOMC.EventVertexGenerators.VtxSmearedRealistic25ns900GeV2021Collision_cfi',
+    'Realistic25ns13p6TeVEarly2022Collision' : 'IOMC.EventVertexGenerators.VtxSmearedRealistic25ns13p6TeVEarly2022Collision_cfi',
 }
 VtxSmearedDefaultKey='Realistic50ns13TeVCollision'
 VtxSmearedHIDefaultKey='RealisticPbPbCollision2018'
diff --git a/IOMC/EventVertexGenerators/python/VtxSmearedParameters_cfi.py b/IOMC/EventVertexGenerators/python/VtxSmearedParameters_cfi.py
index 76e9ca25e26a4..2e050bc605690 100644
--- a/IOMC/EventVertexGenerators/python/VtxSmearedParameters_cfi.py
+++ b/IOMC/EventVertexGenerators/python/VtxSmearedParameters_cfi.py
@@ -780,6 +780,38 @@
     Z0 = cms.double(0.423776)
 )
 
+# From first Run 3 data at 13.6 TeV and 3.8T
+# BS parameters extracted from run 355100, fill 7920:
+# X0         =  0.172394 [cm]
+# Y0         = -0.180946 [cm]
+# Z0         =  0.94181  [cm]
+# sigmaZ0    =  3.81941  [cm]
+# BeamWidthX = 0.0008772 [cm]
+# BeamWidthY = 0.0010078 [cm]
+#
+# set SigmaZ0 = 3.8 [cm]
+# set BeamWidthX = BeamWidthY = 10.0 [um]
+# set beta* = 30 cm
+# energy = 13.6 TeV
+# From LHC calculator, emittance is 6.621e-8 cm
+# https://lpc.web.cern.ch/lumiCalc.html
+#
+# BPIX absolute position (https://twiki.cern.ch/twiki/bin/view/CMS/TkAlignmentPixelPosition?rev=42#2022):
+# X = -0.01955 cm
+# Y = -0.1583  cm
+# Z = -0.2626  cm
+Realistic25ns13p6TeVEarly2022CollisionVtxSmearingParameters = cms.PSet(
+    Phi = cms.double(0.0),
+    BetaStar = cms.double(30.0),
+    Emittance = cms.double(6.621e-8),
+    Alpha = cms.double(0.0),
+    SigmaZ = cms.double(3.8),
+    TimeOffset = cms.double(0.0),
+    X0 = cms.double(0.191944),
+    Y0 = cms.double(-0.022646),
+    Z0 = cms.double(1.20441)
+)
+
 # Test HF offset
 ShiftedCollision2015VtxSmearingParameters = cms.PSet(
     Phi = cms.double(0.0),
diff --git a/IOMC/EventVertexGenerators/python/VtxSmearedRealistic25ns13p6TeVEarly2022Collision_cfi.py b/IOMC/EventVertexGenerators/python/VtxSmearedRealistic25ns13p6TeVEarly2022Collision_cfi.py
new file mode 100644
index 0000000000000..af695b6ca5a5b
--- /dev/null
+++ b/IOMC/EventVertexGenerators/python/VtxSmearedRealistic25ns13p6TeVEarly2022Collision_cfi.py
@@ -0,0 +1,7 @@
+import FWCore.ParameterSet.Config as cms
+
+from IOMC.EventVertexGenerators.VtxSmearedParameters_cfi import Realistic25ns13p6TeVEarly2022CollisionVtxSmearingParameters,VtxSmearedCommon
+VtxSmeared = cms.EDProducer("BetafuncEvtVtxGenerator",
+    Realistic25ns13p6TeVEarly2022CollisionVtxSmearingParameters,
+    VtxSmearedCommon
+)