diff --git a/browser/ui/webui/brave_rewards_ui.cc b/browser/ui/webui/brave_rewards_ui.cc
index e66dcb19fd28..61b94607d853 100644
--- a/browser/ui/webui/brave_rewards_ui.cc
+++ b/browser/ui/webui/brave_rewards_ui.cc
@@ -1231,7 +1231,9 @@ void RewardsDOMHandler::SaveAdsSetting(const base::ListValue* args) {
   const std::string value = args->GetList()[1].GetString();
 
   if (key == "adsEnabled") {
-    ads_service_->SetEnabled(value == "true");
+    const auto is_enabled =
+        value == "true" && ads_service_->IsSupportedRegion();
+    ads_service_->SetEnabled(is_enabled);
   } else if (key == "adsPerHour") {
     ads_service_->SetAdsPerHour(std::stoull(value));
   }
diff --git a/components/brave_ads/browser/ads_service_impl.cc b/components/brave_ads/browser/ads_service_impl.cc
index 2e8df5ba7bb6..66e4dc7ae455 100644
--- a/components/brave_ads/browser/ads_service_impl.cc
+++ b/components/brave_ads/browser/ads_service_impl.cc
@@ -1270,8 +1270,8 @@ void AdsServiceImpl::MigratePrefsVersion1To2() {
 }
 
 void AdsServiceImpl::MigratePrefsVersion2To3() {
-  auto locale = GetLocale();
-  auto region = ads::Ads::GetRegion(locale);
+  const auto locale = GetLocale();
+  const auto region = ads::Ads::GetRegion(locale);
 
   // Disable ads if upgrading from a pre brave ads build due to a bug where ads
   // were always enabled
@@ -1279,7 +1279,7 @@ void AdsServiceImpl::MigratePrefsVersion2To3() {
 
   // Disable ads for unsupported legacy regions due to a bug where ads were
   // enabled even if the users region was not supported
-  std::vector<std::string> legacy_regions = {
+  const std::vector<std::string> legacy_regions = {
     "US",  // United States of America
     "CA",  // Canada
     "GB",  // United Kingdom (Great Britain and Northern Ireland)
@@ -1290,7 +1290,7 @@ void AdsServiceImpl::MigratePrefsVersion2To3() {
   DisableAdsForUnsupportedRegions(region, legacy_regions);
 
   // On-board users for newly supported regions
-  std::vector<std::string> new_regions = {
+  const std::vector<std::string> new_regions = {
     "AU",  // Australia
     "NZ",  // New Zealand
     "IE"   // Ireland
@@ -1300,11 +1300,26 @@ void AdsServiceImpl::MigratePrefsVersion2To3() {
 }
 
 void AdsServiceImpl::MigratePrefsVersion3To4() {
-  auto locale = GetLocale();
-  auto region = ads::Ads::GetRegion(locale);
+  const auto locale = GetLocale();
+  const auto region = ads::Ads::GetRegion(locale);
+
+  // Disable ads for unsupported legacy regions due to a bug where ads were
+  // enabled even if the users region was not supported
+  const std::vector<std::string> legacy_regions = {
+    "US",  // United States of America
+    "CA",  // Canada
+    "GB",  // United Kingdom (Great Britain and Northern Ireland)
+    "DE",  // Germany
+    "FR",  // France
+    "AU",  // Australia
+    "NZ",  // New Zealand
+    "IE"   // Ireland
+  };
+
+  DisableAdsForUnsupportedRegions(region, legacy_regions);
 
   // On-board users for newly supported regions
-  std::vector<std::string> new_regions = {
+  const std::vector<std::string> new_regions = {
     "AR",  // Argentina
     "AT",  // Austria
     "BR",  // Brazil