diff --git a/recipes/annosine2/meta.yaml b/recipes/annosine2/meta.yaml
new file mode 100644
index 0000000000000..9c474c8c73b80
--- /dev/null
+++ b/recipes/annosine2/meta.yaml
@@ -0,0 +1,59 @@
+{% set name = "annosine2" %}
+{% set version = "1.0.4" %}
+
+package:
+  name: "{{ name|lower }}"
+  version: "{{ version }}"
+
+source:
+  url: https://pypi.io/packages/source/{{ name[0] }}/{{ name }}/{{ name }}-{{ version }}.tar.gz
+  sha256: c9d12adec9875c4a429c6e9da5b76d31c760ef7474635caf742d25592378f34c
+
+build:
+  number: 0
+  entry_points:
+    - annosine2 = AnnoSINE.AnnoSINE_v2:main
+  script: "{{ PYTHON }} -m pip install . --no-deps --ignore-installed -vvv "
+  run_exports:
+        - {{ pin_subpackage('annosine2', max_pin="x") }}
+  noarch: python
+
+requirements:
+  host:
+    - pip
+    - python
+  run:
+    - cycler ==0.10.0
+    - kiwisolver
+    - matplotlib-base
+    - numpy
+    - pillow
+    - pyparsing
+    - python
+    - python-dateutil
+    - six
+    - hmmer ==3.3.1
+    - minimap2 ==2.26
+    - nodejs ==18.12.1
+    - trf ==4.09
+    - irf ==3.08
+    - cd-hit ==4.8.1
+    - repeatmasker ==4.1.2.p1
+    - seqtk ==1.4
+
+
+test:
+  imports:
+    - AnnoSINE
+  commands:
+    - annosine2 --help
+
+about:
+  home: https://github.com/liaoherui/AnnoSINE
+  license: MIT
+  license_family: MIT
+  summary: AnnoSINE2 - SINE Annotation Tool for Plant and Animal Genomes
+
+extra:
+  recipe-maintainers:
+    - liaoherui