diff --git a/packages/@jsii/python-runtime/requirements.txt b/packages/@jsii/python-runtime/requirements.txt
index 54d921ccb0..6d6278e958 100644
--- a/packages/@jsii/python-runtime/requirements.txt
+++ b/packages/@jsii/python-runtime/requirements.txt
@@ -3,7 +3,7 @@ mypy==1.11.1
 pip~=24.2
 pytest~=8.3
 pytest-mypy~=0.10
-setuptools~=71.1.0
+setuptools~=73.0.1
 types-python-dateutil~=2.9
 wheel~=0.44