diff --git a/guide/index.rst b/guide/index.rst
index 12fb7e2..0e0266b 100644
--- a/guide/index.rst
+++ b/guide/index.rst
@@ -1006,6 +1006,7 @@ Response Config Options
                 'csp' => [],
                 'csp_report_only' => [],
                 'json_flags' => null,
+                'replace_headers' => false,
                 'request_instance' => 'default',
             ],
         ],
@@ -1065,6 +1066,11 @@ json_flags
 
 Flags for ``json_encode``. The default is set to none.
 
+replace_headers
+"""""""""""""""
+
+Set ``true`` to force header replacement. Default is ``false`` to not replace.
+
 request_instance
 """"""""""""""""
 
diff --git a/src/App.php b/src/App.php
index 6845409..d597093 100644
--- a/src/App.php
+++ b/src/App.php
@@ -1256,6 +1256,9 @@ protected static function setResponse(string $instance) : Response
         if (isset($config['json_flags'])) {
             $service->setJsonFlags($config['json_flags']);
         }
+        if (isset($config['replace_headers'])) {
+            $service->setReplaceHeaders($config['replace_headers']);
+        }
         return static::setService('response', $service, $instance);
     }
 
diff --git a/tests/configs/response.config.php b/tests/configs/response.config.php
index 629beac..43d0ee3 100644
--- a/tests/configs/response.config.php
+++ b/tests/configs/response.config.php
@@ -39,6 +39,7 @@
             ],
         ],
         'json_flags' => \JSON_THROW_ON_ERROR,
+        'replace_headers' => false,
         'request_instance' => 'default',
     ],
 ];