diff --git a/src/relay/backend/aot/aot_lower_main.cc b/src/relay/backend/aot/aot_lower_main.cc
index a97f7bcaa64a..5bfe7cb8e749 100644
--- a/src/relay/backend/aot/aot_lower_main.cc
+++ b/src/relay/backend/aot/aot_lower_main.cc
@@ -417,7 +417,7 @@ class AOTMainLowerer : public MixedModeVisitor {
    * runner function needs to be legalized by the LegalizePackedCalls pass.
    */
   tir::PrimFunc CreateMainFunc(String mod_name) {
-    tir::Stmt body = tir::SeqStmt(stmts_);
+    tir::Stmt body = tir::SeqStmt::Flatten(stmts_);
     // Allocate the sids
     std::unordered_map<int, bool> allocated;
     std::vector<std::pair<int64_t, int64_t>> sids_to_allocate;
@@ -717,7 +717,7 @@ class AOTMainLowerer : public MixedModeVisitor {
                                         {tvm::tir::StringImm(device_hook_name), context})));
       device_hooks.push_back(device_hook);
     }
-    return tir::SeqStmt(device_hooks);
+    return tir::SeqStmt::Flatten(device_hooks);
   }
 
   /*!
diff --git a/src/tir/contrib/ethosu/passes.cc b/src/tir/contrib/ethosu/passes.cc
index 369c4adc8536..5968febe9af0 100644
--- a/src/tir/contrib/ethosu/passes.cc
+++ b/src/tir/contrib/ethosu/passes.cc
@@ -144,7 +144,7 @@ class HoistAllocatesMutator : public StmtExprMutator {
     for (auto it = allocates_.rbegin(); it != allocates_.rend(); it++) {
       Allocate current_alloc = *it;
       if (it != allocates_.rbegin()) {
-        new_main_func_body = SeqStmt({new_main_func_body});
+        new_main_func_body = SeqStmt::Flatten(new_main_func_body);
       }
       new_main_func_body =
           Allocate(current_alloc->buffer_var, current_alloc->dtype, current_alloc->extents,
diff --git a/tests/cpp/ir_functor_test.cc b/tests/cpp/ir_functor_test.cc
index 727b07c2e488..30b1bc78247a 100644
--- a/tests/cpp/ir_functor_test.cc
+++ b/tests/cpp/ir_functor_test.cc
@@ -295,7 +295,7 @@ TEST(IRF, StmtMutator) {
     Stmt body2 = Evaluate(1);
     auto* extentptr = body.as<AllocateNode>()->extents.get();
     // construct a recursive SeqStmt.
-    body = SeqStmt({body});
+    body = SeqStmt({body, body2});
     auto bref = body;
     body = SeqStmt({body, body2});
     body = v(std::move(body));