diff --git a/packages/block-library/src/block/block.json b/packages/block-library/src/block/block.json
index d6630177fc685..4cb53960725d2 100644
--- a/packages/block-library/src/block/block.json
+++ b/packages/block-library/src/block/block.json
@@ -5,7 +5,7 @@
 	"title": "Pattern",
 	"category": "reusable",
 	"description": "Create and save content to reuse across your site. Update the pattern, and the changes apply everywhere it’s used.",
- 	"keywords": [ "reusable" ],
+	"keywords": [ "reusable" ],
 	"textdomain": "default",
 	"attributes": {
 		"ref": {
diff --git a/packages/components/CHANGELOG.md b/packages/components/CHANGELOG.md
index a5f163a623e39..1e7e654ac1c81 100644
--- a/packages/components/CHANGELOG.md
+++ b/packages/components/CHANGELOG.md
@@ -9,7 +9,8 @@
 
 ### Bug Fix
 
--   `Popover`: Pin `react-dropdown-menu` version to avoid breaking changes in dependency updates. ([52356](https://github.com/WordPress/gutenberg/pull/52356)).
+-   `Popover`: Pin `react-dropdown-menu` version to avoid breaking changes in dependency updates. ([#52356](https://github.com/WordPress/gutenberg/pull/52356)).
+-   `Item`: Unify focus style and add default font styles. ([#52495](https://github.com/WordPress/gutenberg/pull/52495)).
 
 ## 25.3.0 (2023-07-05)
 
diff --git a/packages/components/src/item-group/item/hook.ts b/packages/components/src/item-group/item/hook.ts
index bd3be96c618b8..ff97e3adae160 100644
--- a/packages/components/src/item-group/item/hook.ts
+++ b/packages/components/src/item-group/item/hook.ts
@@ -42,7 +42,8 @@ export function useItem( props: WordPressComponentProps< ItemProps, 'div' > ) {
 	const classes = useMemo(
 		() =>
 			cx(
-				as === 'button' && styles.unstyledButton,
+				( as === 'button' || as === 'a' ) &&
+					styles.unstyledButton( as ),
 				styles.itemSizes[ size ] || styles.itemSizes.medium,
 				styles.item,
 				spacedAround && styles.spacedAround,
diff --git a/packages/components/src/item-group/stories/index.tsx b/packages/components/src/item-group/stories/index.tsx
index 3fa35c67cfb53..e520ff10c160f 100644
--- a/packages/components/src/item-group/stories/index.tsx
+++ b/packages/components/src/item-group/stories/index.tsx
@@ -39,20 +39,25 @@ Default.args = {
 	children: (
 		[
 			{
-				children: 'First item',
+				children: 'First button item',
 				// eslint-disable-next-line no-alert
 				onClick: () => alert( 'First item clicked' ),
 			},
 			{
-				children: 'Second item',
+				children: 'Second button item',
 				// eslint-disable-next-line no-alert
 				onClick: () => alert( 'Second item clicked' ),
 			},
 			{
-				children: 'Third item',
+				children: 'Third button item',
 				// eslint-disable-next-line no-alert
 				onClick: () => alert( 'Third item clicked' ),
 			},
+			{
+				children: 'Anchor item',
+				as: 'a',
+				href: 'https://wordpress.org',
+			},
 		] as ItemProps[]
 	 ).map( mapPropsToItem ),
 };
diff --git a/packages/components/src/item-group/styles.ts b/packages/components/src/item-group/styles.ts
index 670fdf987dd93..95076f0bb4081 100644
--- a/packages/components/src/item-group/styles.ts
+++ b/packages/components/src/item-group/styles.ts
@@ -6,34 +6,45 @@ import { css } from '@emotion/react';
 /**
  * Internal dependencies
  */
-import { CONFIG, COLORS } from '../utils';
-
-export const unstyledButton = css`
-	appearance: none;
-	border: 1px solid transparent;
-	cursor: pointer;
-	background: none;
-	text-align: start;
-
-	svg,
-	path {
-		fill: currentColor;
-	}
-
-	&:hover {
-		color: ${ COLORS.ui.theme };
-	}
-
-	&:focus-visible {
-		box-shadow: 0 0 0 var( --wp-admin-border-width-focus )
-			var(
-				--wp-components-color-accent,
-				var( --wp-admin-theme-color, ${ COLORS.ui.theme } )
-			);
-		// Windows high contrast mode.
-		outline: 2px solid transparent;
-	}
-`;
+import { CONFIG, COLORS, font } from '../utils';
+
+export const unstyledButton = ( as: 'a' | 'button' ) => {
+	return css`
+		font-size: ${ font( 'default.fontSize' ) };
+		font-family: inherit;
+		appearance: none;
+		border: 1px solid transparent;
+		cursor: pointer;
+		background: none;
+		text-align: start;
+		text-decoration: ${ as === 'a' ? 'none' : undefined };
+
+		svg,
+		path {
+			fill: currentColor;
+		}
+
+		&:hover {
+			color: ${ COLORS.ui.theme };
+		}
+
+		&:focus {
+			box-shadow: none;
+			outline: none;
+		}
+
+		&:focus-visible {
+			box-shadow: 0 0 0 var( --wp-admin-border-width-focus )
+				var(
+					--wp-components-color-accent,
+					var( --wp-admin-theme-color, ${ COLORS.ui.theme } )
+				);
+			// Windows high contrast mode.
+			outline: 2px solid transparent;
+			outline-offset: 0;
+		}
+	`;
+};
 
 export const itemWrapper = css`
 	width: 100%;
diff --git a/packages/edit-post/src/components/preferences-modal/test/__snapshots__/index.js.snap b/packages/edit-post/src/components/preferences-modal/test/__snapshots__/index.js.snap
index 182531ee01c02..32254bb91c695 100644
--- a/packages/edit-post/src/components/preferences-modal/test/__snapshots__/index.js.snap
+++ b/packages/edit-post/src/components/preferences-modal/test/__snapshots__/index.js.snap
@@ -590,6 +590,8 @@ exports[`EditPostPreferencesModal should match snapshot when the modal is active
 }
 
 .emotion-13 {
+  font-size: 13px;
+  font-family: inherit;
   -webkit-appearance: none;
   -moz-appearance: none;
   -ms-appearance: none;
@@ -616,12 +618,18 @@ exports[`EditPostPreferencesModal should match snapshot when the modal is active
   color: var(--wp-components-color-accent, var(--wp-admin-theme-color, #3858e9));
 }
 
+.emotion-13:focus {
+  box-shadow: none;
+  outline: none;
+}
+
 .emotion-13:focus-visible {
   box-shadow: 0 0 0 var( --wp-admin-border-width-focus ) var(
-  				--wp-components-color-accent,
-  				var( --wp-admin-theme-color, var(--wp-components-color-accent, var(--wp-admin-theme-color, #3858e9)) )
-  			);
+  					--wp-components-color-accent,
+  					var( --wp-admin-theme-color, var(--wp-components-color-accent, var(--wp-admin-theme-color, #3858e9)) )
+  				);
   outline: 2px solid transparent;
+  outline-offset: 0;
 }
 
 .emotion-15 {
diff --git a/packages/edit-site/src/components/sidebar-navigation-item/style.scss b/packages/edit-site/src/components/sidebar-navigation-item/style.scss
index 14dbc54efe523..88ff27a9c1d2f 100644
--- a/packages/edit-site/src/components/sidebar-navigation-item/style.scss
+++ b/packages/edit-site/src/components/sidebar-navigation-item/style.scss
@@ -26,22 +26,6 @@
 		fill: $gray-600;
 	}
 
-	&:is(a) {
-		text-decoration: none;
-		display: flex;
-		align-items: center;
-
-		&:focus {
-			box-shadow: none;
-			outline: none;
-		}
-
-		&:focus-visible {
-			box-shadow: 0 0 0 var(--wp-admin-border-width-focus) var(--wp-admin-theme-color);
-			outline: 2px solid transparent;
-		}
-	}
-
 	&.with-suffix {
 		padding-right: $grid-unit-20;
 	}