diff --git a/packages/block-editor/src/hooks/duotone.js b/packages/block-editor/src/hooks/duotone.js
index 163846d52e415a..27866f580d7373 100644
--- a/packages/block-editor/src/hooks/duotone.js
+++ b/packages/block-editor/src/hooks/duotone.js
@@ -60,82 +60,109 @@ export function getValuesFromColors( colors = [] ) {
  */
 
 /**
- * SVG and stylesheet needed for rendering the duotone filter.
+ * Stylesheet for rendering the duotone filter.
  *
  * @param {Object} props          Duotone props.
  * @param {string} props.selector Selector to apply the filter to.
  * @param {string} props.id       Unique id for this duotone filter.
- * @param {Values} props.values   R, G, B, and A values to filter with.
  *
  * @return {WPElement} Duotone element.
  */
-function DuotoneFilter( { selector, id, values } ) {
-	const stylesheet = `
+function DuotoneStylesheet( { selector, id } ) {
+	const css = `
 ${ selector } {
 	filter: url( #${ id } );
 }
 `;
+	return <style>{ css }</style>;
+}
 
+/**
+ * SVG for rendering the duotone filter.
+ *
+ * @param {Object} props        Duotone props.
+ * @param {string} props.id     Unique id for this duotone filter.
+ * @param {Values} props.values R, G, B, and A values to filter with.
+ *
+ * @return {WPElement} Duotone element.
+ */
+function DuotoneFilter( { id, values } ) {
 	return (
-		<>
-			<SVG
-				xmlnsXlink="http://www.w3.org/1999/xlink"
-				viewBox="0 0 0 0"
-				width="0"
-				height="0"
-				focusable="false"
-				role="none"
-				style={ {
-					visibility: 'hidden',
-					position: 'absolute',
-					left: '-9999px',
-					overflow: 'hidden',
-				} }
-			>
-				<defs>
-					<filter id={ id }>
-						<feColorMatrix
-							// Use sRGB instead of linearRGB so transparency looks correct.
-							colorInterpolationFilters="sRGB"
-							type="matrix"
-							// Use perceptual brightness to convert to grayscale.
-							values="
-								.299 .587 .114 0 0
-								.299 .587 .114 0 0
-								.299 .587 .114 0 0
-								.299 .587 .114 0 0
-							"
+		<SVG
+			xmlnsXlink="http://www.w3.org/1999/xlink"
+			viewBox="0 0 0 0"
+			width="0"
+			height="0"
+			focusable="false"
+			role="none"
+			style={ {
+				visibility: 'hidden',
+				position: 'absolute',
+				left: '-9999px',
+				overflow: 'hidden',
+			} }
+		>
+			<defs>
+				<filter id={ id }>
+					<feColorMatrix
+						// Use sRGB instead of linearRGB so transparency looks correct.
+						colorInterpolationFilters="sRGB"
+						type="matrix"
+						// Use perceptual brightness to convert to grayscale.
+						values="
+							.299 .587 .114 0 0
+							.299 .587 .114 0 0
+							.299 .587 .114 0 0
+							.299 .587 .114 0 0
+						"
+					/>
+					<feComponentTransfer
+						// Use sRGB instead of linearRGB to be consistent with how CSS gradients work.
+						colorInterpolationFilters="sRGB"
+					>
+						<feFuncR
+							type="table"
+							tableValues={ values.r.join( ' ' ) }
+						/>
+						<feFuncG
+							type="table"
+							tableValues={ values.g.join( ' ' ) }
+						/>
+						<feFuncB
+							type="table"
+							tableValues={ values.b.join( ' ' ) }
 						/>
-						<feComponentTransfer
-							// Use sRGB instead of linearRGB to be consistent with how CSS gradients work.
-							colorInterpolationFilters="sRGB"
-						>
-							<feFuncR
-								type="table"
-								tableValues={ values.r.join( ' ' ) }
-							/>
-							<feFuncG
-								type="table"
-								tableValues={ values.g.join( ' ' ) }
-							/>
-							<feFuncB
-								type="table"
-								tableValues={ values.b.join( ' ' ) }
-							/>
-							<feFuncA
-								type="table"
-								tableValues={ values.a.join( ' ' ) }
-							/>
-						</feComponentTransfer>
-						<feComposite
-							// Re-mask the image with the original transparency since the feColorMatrix above loses that information.
-							in2="SourceGraphic"
-							operator="in"
+						<feFuncA
+							type="table"
+							tableValues={ values.a.join( ' ' ) }
 						/>
-					</filter>
-				</defs>
-			</SVG>
-			<style dangerouslySetInnerHTML={ { __html: stylesheet } } />
+					</feComponentTransfer>
+					<feComposite
+						// Re-mask the image with the original transparency since the feColorMatrix above loses that information.
+						in2="SourceGraphic"
+						operator="in"
+					/>
+				</filter>
+			</defs>
+		</SVG>
+	);
+}
+
+/**
+ * SVG and stylesheet needed for rendering the duotone filter.
+ *
+ * @param {Object} props          Duotone props.
+ * @param {string} props.selector Selector to apply the filter to.
+ * @param {string} props.id       Unique id for this duotone filter.
+ * @param {Values} props.values   R, G, B, and A values to filter with.
+ *
+ * @return {WPElement} Duotone element.
+ */
+function InlineDuotone( { selector, id, values } ) {
+	return (
+		<>
+			<DuotoneFilter id={ id } values={ values } />
+			<DuotoneStylesheet id={ id } selector={ selector } />
 		</>
 	);
 }
@@ -321,7 +348,7 @@ const withDuotoneStyles = createHigherOrderComponent(
 			<>
 				{ element &&
 					createPortal(
-						<DuotoneFilter
+						<InlineDuotone
 							selector={ selectorsGroup }
 							id={ id }
 							values={ getValuesFromColors( values ) }
@@ -335,6 +362,15 @@ const withDuotoneStyles = createHigherOrderComponent(
 	'withDuotoneStyles'
 );
 
+export function PresetDuotoneFilter( { preset } ) {
+	return (
+		<DuotoneFilter
+			id={ `wp-duotone-${ preset.slug }` }
+			values={ getValuesFromColors( preset.colors ) }
+		/>
+	);
+}
+
 addFilter(
 	'blocks.registerBlockType',
 	'core/editor/duotone/add-attributes',
diff --git a/packages/block-editor/src/hooks/index.js b/packages/block-editor/src/hooks/index.js
index 708dae62a39714..3b25875878a56e 100644
--- a/packages/block-editor/src/hooks/index.js
+++ b/packages/block-editor/src/hooks/index.js
@@ -19,3 +19,4 @@ export { getBorderClassesAndStyles, useBorderProps } from './use-border-props';
 export { getColorClassesAndStyles, useColorProps } from './use-color-props';
 export { getSpacingClassesAndStyles } from './use-spacing-props';
 export { useCachedTruthy } from './use-cached-truthy';
+export { PresetDuotoneFilter } from './duotone';
diff --git a/packages/block-editor/src/index.js b/packages/block-editor/src/index.js
index 0672b0c0fbfddf..078895c2c5a02d 100644
--- a/packages/block-editor/src/index.js
+++ b/packages/block-editor/src/index.js
@@ -3,6 +3,7 @@
  */
 import './hooks';
 export {
+	PresetDuotoneFilter as __unstablePresetDuotoneFilter,
 	getBorderClassesAndStyles as __experimentalGetBorderClassesAndStyles,
 	useBorderProps as __experimentalUseBorderProps,
 	getColorClassesAndStyles as __experimentalGetColorClassesAndStyles,
diff --git a/packages/blocks/src/api/constants.js b/packages/blocks/src/api/constants.js
index c9b8d3e0e8f1d3..d8d02d7567862a 100644
--- a/packages/blocks/src/api/constants.js
+++ b/packages/blocks/src/api/constants.js
@@ -56,6 +56,10 @@ export const __EXPERIMENTAL_STYLE_PROPERTY = {
 		support: [ 'color', 'text' ],
 		requiresOptOut: true,
 	},
+	filter: {
+		value: [ 'filter', 'duotone' ],
+		support: [ 'color', '__experimentalDuotone' ],
+	},
 	linkColor: {
 		value: [ 'elements', 'link', 'color', 'text' ],
 		support: [ 'color', 'link' ],
diff --git a/packages/edit-site/src/components/block-editor/resizable-editor.js b/packages/edit-site/src/components/block-editor/resizable-editor.js
index 91dee707ccd757..ce9e0d1bdec6b1 100644
--- a/packages/edit-site/src/components/block-editor/resizable-editor.js
+++ b/packages/edit-site/src/components/block-editor/resizable-editor.js
@@ -36,7 +36,7 @@ const HANDLE_STYLES_OVERRIDE = {
 	left: undefined,
 };
 
-function ResizableEditor( { enableResizing, settings, ...props } ) {
+function ResizableEditor( { enableResizing, settings, children, ...props } ) {
 	const deviceType = useSelect(
 		( select ) =>
 			select( editSiteStore ).__experimentalGetPreviewDeviceType(),
@@ -182,7 +182,11 @@ function ResizableEditor( { enableResizing, settings, ...props } ) {
 				name="editor-canvas"
 				className="edit-site-visual-editor__editor-canvas"
 				{ ...props }
-			/>
+			>
+				{ /* Filters need to be rendered before children to avoid Safari rendering issues. */ }
+				{ settings.svgFilters }
+				{ children }
+			</Iframe>
 		</ResizableBox>
 	);
 }
diff --git a/packages/edit-site/src/components/editor/global-styles-renderer.js b/packages/edit-site/src/components/editor/global-styles-renderer.js
index 3abcb1813fd572..9af00a7da6775a 100644
--- a/packages/edit-site/src/components/editor/global-styles-renderer.js
+++ b/packages/edit-site/src/components/editor/global-styles-renderer.js
@@ -20,7 +20,7 @@ import { store as editSiteStore } from '../../store';
 import { useGlobalStylesOutput } from '../global-styles/use-global-styles-output';
 
 function useGlobalStylesRenderer() {
-	const [ styles, settings ] = useGlobalStylesOutput();
+	const [ styles, settings, svgFilters ] = useGlobalStylesOutput();
 	const { getSettings } = useSelect( editSiteStore );
 	const { updateSettings } = useDispatch( editSiteStore );
 
@@ -37,6 +37,7 @@ function useGlobalStylesRenderer() {
 		updateSettings( {
 			...currentStoreSettings,
 			styles: [ ...nonGlobalStyles, ...styles ],
+			svgFilters,
 			__experimentalFeatures: settings,
 		} );
 	}, [ styles, settings ] );
diff --git a/packages/edit-site/src/components/global-styles/use-global-styles-output.js b/packages/edit-site/src/components/global-styles/use-global-styles-output.js
index 72ed5a5afe32e4..9584b8b2f77b30 100644
--- a/packages/edit-site/src/components/global-styles/use-global-styles-output.js
+++ b/packages/edit-site/src/components/global-styles/use-global-styles-output.js
@@ -24,6 +24,7 @@ import {
 } from '@wordpress/blocks';
 import { useEffect, useState, useContext } from '@wordpress/element';
 import { getCSSRules } from '@wordpress/style-engine';
+import { __unstablePresetDuotoneFilter as PresetDuotoneFilter } from '@wordpress/block-editor';
 
 /**
  * Internal dependencies
@@ -59,16 +60,27 @@ function compileStyleValue( uncompiledValue ) {
 function getPresetsDeclarations( blockPresets = {} ) {
 	return reduce(
 		PRESET_METADATA,
-		( declarations, { path, valueKey, cssVarInfix } ) => {
+		( declarations, { path, valueKey, valueFunc, cssVarInfix } ) => {
 			const presetByOrigin = get( blockPresets, path, [] );
 			[ 'default', 'theme', 'custom' ].forEach( ( origin ) => {
 				if ( presetByOrigin[ origin ] ) {
 					presetByOrigin[ origin ].forEach( ( value ) => {
-						declarations.push(
-							`--wp--preset--${ cssVarInfix }--${ kebabCase(
-								value.slug
-							) }: ${ value[ valueKey ] }`
-						);
+						if ( valueKey ) {
+							declarations.push(
+								`--wp--preset--${ cssVarInfix }--${ kebabCase(
+									value.slug
+								) }: ${ value[ valueKey ] }`
+							);
+						} else if (
+							valueFunc &&
+							typeof valueFunc === 'function'
+						) {
+							declarations.push(
+								`--wp--preset--${ cssVarInfix }--${ kebabCase(
+									value.slug
+								) }: ${ valueFunc( value ) }`
+							);
+						}
 					} );
 				}
 			} );
@@ -123,6 +135,25 @@ function getPresetsClasses( blockSelector, blockPresets = {} ) {
 	);
 }
 
+function getPresetsSvgFilters( blockPresets = {} ) {
+	return PRESET_METADATA.filter(
+		// Duotone are the only type of filters for now.
+		( metadata ) => metadata.path.at( -1 ) === 'duotone'
+	).flatMap( ( metadata ) => {
+		const presetByOrigin = get( blockPresets, metadata.path, {} );
+		return [ 'default', 'theme' ]
+			.filter( ( origin ) => presetByOrigin[ origin ] )
+			.flatMap( ( origin ) =>
+				presetByOrigin[ origin ].map( ( preset ) => (
+					<PresetDuotoneFilter
+						preset={ preset }
+						key={ preset.slug }
+					/>
+				) )
+			);
+	} );
+}
+
 function flattenTree( input = {}, prefix, token ) {
 	let result = [];
 	Object.keys( input ).forEach( ( key ) => {
@@ -215,7 +246,9 @@ export const getNodesWithStyles = ( tree, blockSelectors ) => {
 
 	const pickStyleKeys = ( treeToPickFrom ) =>
 		pickBy( treeToPickFrom, ( value, key ) =>
-			[ 'border', 'color', 'spacing', 'typography' ].includes( key )
+			[ 'border', 'color', 'spacing', 'typography', 'filter' ].includes(
+				key
+			)
 		);
 
 	// Top-level.
@@ -242,6 +275,7 @@ export const getNodesWithStyles = ( tree, blockSelectors ) => {
 			nodes.push( {
 				styles: blockStyles,
 				selector: blockSelectors[ blockName ].selector,
+				duotoneSelector: blockSelectors[ blockName ].duotoneSelector,
 			} );
 		}
 
@@ -333,9 +367,34 @@ export const toStyles = ( tree, blockSelectors ) => {
 	const nodesWithStyles = getNodesWithStyles( tree, blockSelectors );
 	const nodesWithSettings = getNodesWithSettings( tree, blockSelectors );
 
-	let ruleset =
-		'.wp-site-blocks > * { margin-top: 0; margin-bottom: 0; }.wp-site-blocks > * + * { margin-top: var( --wp--style--block-gap ); }';
-	nodesWithStyles.forEach( ( { selector, styles } ) => {
+	/*
+	 * Reset default browser margin on the root body element.
+	 * This is set on the root selector **before** generating the ruleset
+	 * from the `theme.json`. This is to ensure that if the `theme.json` declares
+	 * `margin` in its `spacing` declaration for the `body` element then these
+	 * user-generated values take precedence in the CSS cascade.
+	 * @link https://github.com/WordPress/gutenberg/issues/36147.
+	 */
+	let ruleset = 'body {margin: 0;}';
+	nodesWithStyles.forEach( ( { selector, duotoneSelector, styles } ) => {
+		const duotoneStyles = {};
+		if ( styles?.filter ) {
+			duotoneStyles.filter = styles.filter;
+			delete styles.filter;
+		}
+
+		// Process duotone styles (they use color.__experimentalDuotone selector).
+		if ( duotoneSelector ) {
+			const duotoneDeclarations = getStylesDeclarations( duotoneStyles );
+			if ( duotoneDeclarations.length === 0 ) {
+				return;
+			}
+			ruleset =
+				ruleset +
+				`${ duotoneSelector }{${ duotoneDeclarations.join( ';' ) };}`;
+		}
+
+		// Process the remaning block styles (they use either normal block class or __experimentalSelector).
 		const declarations = getStylesDeclarations( styles );
 		if ( declarations.length === 0 ) {
 			return;
@@ -358,6 +417,13 @@ export const toStyles = ( tree, blockSelectors ) => {
 	return ruleset;
 };
 
+export function toSvgFilters( tree, blockSelectors ) {
+	const nodesWithSettings = getNodesWithSettings( tree, blockSelectors );
+	return nodesWithSettings.flatMap( ( { presets } ) => {
+		return getPresetsSvgFilters( presets );
+	} );
+}
+
 const getBlockSelectors = ( blockTypes ) => {
 	const result = {};
 	blockTypes.forEach( ( blockType ) => {
@@ -365,9 +431,12 @@ const getBlockSelectors = ( blockTypes ) => {
 		const selector =
 			blockType?.supports?.__experimentalSelector ??
 			'.wp-block-' + name.replace( 'core/', '' ).replace( '/', '-' );
+		const duotoneSelector =
+			blockType?.supports?.color?.__experimentalDuotone ?? null;
 		result[ name ] = {
 			name,
 			selector,
+			duotoneSelector,
 		};
 	} );
 
@@ -377,6 +446,7 @@ const getBlockSelectors = ( blockTypes ) => {
 export function useGlobalStylesOutput() {
 	const [ stylesheets, setStylesheets ] = useState( [] );
 	const [ settings, setSettings ] = useState( {} );
+	const [ svgFilters, setSvgFilters ] = useState( {} );
 	const { merged: mergedConfig } = useContext( GlobalStylesContext );
 
 	useEffect( () => {
@@ -390,6 +460,7 @@ export function useGlobalStylesOutput() {
 			blockSelectors
 		);
 		const globalStyles = toStyles( mergedConfig, blockSelectors );
+		const filters = toSvgFilters( mergedConfig, blockSelectors );
 		setStylesheets( [
 			{
 				css: customProperties,
@@ -401,7 +472,8 @@ export function useGlobalStylesOutput() {
 			},
 		] );
 		setSettings( mergedConfig.settings );
+		setSvgFilters( filters );
 	}, [ mergedConfig ] );
 
-	return [ stylesheets, settings ];
+	return [ stylesheets, settings, svgFilters ];
 }
diff --git a/packages/edit-site/src/components/global-styles/utils.js b/packages/edit-site/src/components/global-styles/utils.js
index 8f815fd3e3daae..50c412fc06cd59 100644
--- a/packages/edit-site/src/components/global-styles/utils.js
+++ b/packages/edit-site/src/components/global-styles/utils.js
@@ -49,6 +49,12 @@ export const PRESET_METADATA = [
 			},
 		],
 	},
+	{
+		path: [ 'color', 'duotone' ],
+		cssVarInfix: 'duotone',
+		valueFunc: ( { slug } ) => `url( '#wp-duotone-${ slug }' )`,
+		classes: [],
+	},
 	{
 		path: [ 'typography', 'fontSizes' ],
 		valueKey: 'size',