diff --git a/packages/block-editor/src/components/inner-blocks/index.js b/packages/block-editor/src/components/inner-blocks/index.js
index 5233c063ba2094..76f3d70041464f 100644
--- a/packages/block-editor/src/components/inner-blocks/index.js
+++ b/packages/block-editor/src/components/inner-blocks/index.js
@@ -7,7 +7,7 @@ import classnames from 'classnames';
  * WordPress dependencies
  */
 import { useMergeRefs } from '@wordpress/compose';
-import { forwardRef, useMemo } from '@wordpress/element';
+import { forwardRef, useMemo, memo } from '@wordpress/element';
 import { useSelect } from '@wordpress/data';
 import {
 	getBlockSupport,
@@ -42,6 +42,8 @@ function BlockContext( { children, clientId } ) {
 	);
 }
 
+const BlockListItemsMemo = memo( BlockListItems );
+
 /**
  * InnerBlocks is a component which allows a single block to have multiple blocks
  * as children. The UncontrolledInnerBlocks component is used whenever the inner
@@ -117,8 +119,10 @@ function UncontrolledInnerBlocks( props ) {
 		[ defaultLayout, usedLayout, allowSizingOnChildren ]
 	);
 
+	// For controlled inner blocks, we don't want a change in blocks to
+	// re-render the blocks list.
 	const items = (
-		<BlockListItems
+		<BlockListItemsMemo
 			rootClientId={ clientId }
 			renderAppender={ renderAppender }
 			__experimentalAppenderTagName={ __experimentalAppenderTagName }