diff --git a/DESCRIPTION b/DESCRIPTION
index cda3c70f97..b9040db516 100644
--- a/DESCRIPTION
+++ b/DESCRIPTION
@@ -29,5 +29,5 @@ LinkingTo: Rcpp
 Suggests: tinytest, simplermarkdown, curl, bit64, Matrix, palmerpenguins, nycflights13, data.table, tibble
 VignetteBuilder: simplermarkdown
 Roxygen: list(markdown = TRUE)
-RoxygenNote: 7.1.2
+RoxygenNote: 7.2.0
 Encoding: UTF-8
diff --git a/R/QueryCondition.R b/R/QueryCondition.R
index 366bb9aa6e..68faa21c8c 100644
--- a/R/QueryCondition.R
+++ b/R/QueryCondition.R
@@ -1,6 +1,6 @@
 #  MIT License
 #
-#  Copyright (c) 2021 TileDB Inc.
+#  Copyright (c) 2021-2022 TileDB Inc.
 #
 #  Permission is hereby granted, free of charge, to any person obtaining a copy
 #  of this software and associated documentation files (the "Software"), to deal
@@ -37,8 +37,8 @@ setClass("tiledb_query_condition",
 #' @return A 'tiledb_query_condition' object
 #' @export
 tiledb_query_condition <- function(ctx = tiledb_get_context()) {
-    stopifnot(`The argument must be a ctx object` = is(ctx, "tiledb_ctx"),
-              `This function needs TileDB 2.3.0 or newer` = tiledb_version(TRUE) >= "2.3.0")
+    stopifnot("The argument must be a ctx object" = is(ctx, "tiledb_ctx"),
+              "This function needs TileDB 2.3.0 or newer" = tiledb_version(TRUE) >= "2.3.0")
     ptr <- libtiledb_query_condition(ctx@ptr)
     query_condition <- new("tiledb_query_condition", ptr = ptr, init = FALSE)
     invisible(query_condition)
@@ -61,11 +61,11 @@ tiledb_query_condition <- function(ctx = tiledb_get_context()) {
 #' @return The initialized 'tiledb_query_condition' object
 #' @export
 tiledb_query_condition_init <- function(attr, value, dtype, op, qc = tiledb_query_condition()) {
-    stopifnot(`Argument 'qc' with query condition object required` = is(qc, "tiledb_query_condition"),
-              `Argument 'attr' must be character` = is.character(attr),
-              `Argument 'value' must be of length one` = is.vector(value) && all.equal(length(value),1),
-              `Argument 'dtype' must be character` = is.character(dtype),
-              `Argument 'op' must be character` = is.character(op))
+    stopifnot("Argument 'qc' with query condition object required" = is(qc, "tiledb_query_condition"),
+              "Argument 'attr' must be character" = is.character(attr),
+              "Argument 'value' must be of length one" = is.vector(value) && all.equal(length(value),1),
+              "Argument 'dtype' must be character" = is.character(dtype),
+              "Argument 'op' must be character" = is.character(op))
     op <- match.arg(op, c("LT", "LE", "GT", "GE", "EQ", "NE"))
     ## maybe check dtype too
     libtiledb_query_condition_init(qc@ptr, attr, value, dtype, op)
@@ -75,17 +75,18 @@ tiledb_query_condition_init <- function(attr, value, dtype, op, qc = tiledb_quer
 
 #' Combine two 'tiledb_query_condition' objects
 #'
-#' Combines two query condition object using a relatiional operator. Note that at present
-#' only 'AND' is supported.
+#' Combines two query condition object using a relatiional operator. Support for operator
+#' 'AND' is generally available, the 'OR' operator is available if TileDB 2.10 or newer is
+#' used.
 #' @param lhs A 'tiledb_query_condition' object on the left-hand side of the relation
 #' @param rhs A 'tiledb_query_condition' object on the left-hand side of the relation
 #' @param op A character value with then relation, this must be one of 'AND', 'OR' or 'NOT'.
 #' @return The combined 'tiledb_query_condition' object
 #' @export
 tiledb_query_condition_combine <- function(lhs, rhs, op) {
-    stopifnot(`Argument 'lhs' must be a query condition object` = is(lhs, "tiledb_query_condition"),
-              `Argument 'rhs' must be a query condition object` = is(rhs, "tiledb_query_condition"),
-              `Argument 'op' must be a character` = is.character(op))
+    stopifnot("Argument 'lhs' must be a query condition object" = is(lhs, "tiledb_query_condition"),
+              "Argument 'rhs' must be a query condition object" = is(rhs, "tiledb_query_condition"),
+              "Argument 'op' must be a character" = is.character(op))
     op <- match.arg(op, c("AND", "OR", "NOT"))
     qc <- tiledb_query_condition()
     qc@ptr <- libtiledb_query_condition_combine(lhs@ptr, rhs@ptr, op)
diff --git a/inst/tinytest/test_querycondition.R b/inst/tinytest/test_querycondition.R
index 67b834dd11..d64a737d00 100644
--- a/inst/tinytest/test_querycondition.R
+++ b/inst/tinytest/test_querycondition.R
@@ -231,3 +231,56 @@ expect_equal(dim(fullarr), c(50,3))
 subarr <- tiledb_array(uri, as.data.frame=TRUE,
                        query_condition=parse_query_condition(region == "Northeast"))[]
 expect_equal(dim(subarr), c(9,3))
+
+
+## Testing OR condition
+
+## Pre-test: will return NA in case of error ie when TileDB Core does not yet have OR support
+## wrapped in 'class()' to avoid a warning of 'is.na() applied to non-list or vector S4'
+if (is.na(tryCatch(class(qc <- parse_query_condition(x3 == 1 || x4 == 2)), error = function(e) NA)))
+    exit_file("Skipping for lack of 'OR' support in TileDB")
+
+## Re-create penguins
+uri <- tempfile()
+fromDataFrame(penguins, uri, sparse=TRUE)
+
+## Basics
+qc <- tiledb_query_condition_init("year", 2009, "INT32", "EQ")
+arrwithqc <- tiledb_array(uri, as.data.frame=TRUE, query_condition=qc)
+expect_equal(NROW(arrwithqc[]), 120L)
+
+lhs <- tiledb_query_condition_init("year", 2008, "INT32", "GE")
+rhs <- tiledb_query_condition_init("year", 2008, "INT32", "LE")
+qc <- tiledb_query_condition_combine(lhs, rhs, "AND")
+arrwithqc <- tiledb_array(uri, as.data.frame=TRUE, query_condition=qc)
+expect_equal(NROW(arrwithqc[]), 114L)  # basically a different way of writing EQ via '<= && >='
+
+lhs <- tiledb_query_condition_init("year", 2008, "INT32", "GE")
+rhs <- tiledb_query_condition_init("year", 2008, "INT32", "LE")
+qc <- tiledb_query_condition_combine(lhs, rhs, "OR")
+arrwithqc <- tiledb_array(uri, as.data.frame=TRUE, query_condition=qc)
+expect_equal(NROW(arrwithqc[]), 344L)  # the OR makes it unconstrained via '<= || >='
+
+## simple OR
+qc <- parse_query_condition(species == "Adelie" || species == "Chinstrap")
+arr <- tiledb_array(uri, as.data.frame=TRUE, query_condition=qc)
+## Note that in R '||' is used for length-1 comparison, and '|' along a vector so '|' here
+expect_equal(NROW(arr[]), sum(with(penguins, species == "Adelie" | species == "Chinstrap")))
+
+## three elements works too
+qc <- parse_query_condition(species == "Adelie" || species == "Chinstrap" || year >= 2009)
+arr <- tiledb_array(uri, as.data.frame=TRUE, query_condition=qc)
+expect_equal(NROW(arr[]),
+             sum(with(penguins, species == "Adelie" | species == "Chinstrap" | year >= 2009)))
+
+## three elements works too as does mixing AND and OR
+qc <- parse_query_condition(species == "Adelie" || species == "Chinstrap" && year >= 2009)
+arr <- tiledb_array(uri, as.data.frame=TRUE, query_condition=qc)
+expect_equal(NROW(arr[]),
+             sum(with(penguins, species == "Adelie" | species == "Chinstrap" & year >= 2009)))
+
+## empty sets are fine
+qc <- parse_query_condition(year < 2008 || year > 2010)
+arr <- tiledb_array(uri, as.data.frame=TRUE, query_condition=qc)
+expect_equal(NROW(arr[]),
+             sum(with(penguins, year < 2008 | year > 2010)))
diff --git a/man/tiledb_query_condition_combine.Rd b/man/tiledb_query_condition_combine.Rd
index 5604f31c1c..d5321cad95 100644
--- a/man/tiledb_query_condition_combine.Rd
+++ b/man/tiledb_query_condition_combine.Rd
@@ -17,6 +17,7 @@ tiledb_query_condition_combine(lhs, rhs, op)
 The combined 'tiledb_query_condition' object
 }
 \description{
-Combines two query condition object using a relatiional operator. Note that at present
-only 'AND' is supported.
+Combines two query condition object using a relatiional operator. Support for operator
+'AND' is generally available, the 'OR' operator is available if TileDB 2.10 or newer is
+used.
 }