diff --git a/src/build_options.rs b/src/build_options.rs
index 3ee86711b..d05bfa2a7 100644
--- a/src/build_options.rs
+++ b/src/build_options.rs
@@ -564,7 +564,14 @@ impl BuildOptions {
         } else {
             // User given list of interpreters
             let interpreter = if self.interpreter.is_empty() && !target.cross_compiling() {
-                vec![PathBuf::from("python3")]
+                if cfg!(test) {
+                    match env::var_os("MATURIN_TEST_PYTHON") {
+                        Some(python) => vec![python.into()],
+                        None => vec![PathBuf::from("python3")],
+                    }
+                } else {
+                    vec![PathBuf::from("python3")]
+                }
             } else {
                 self.interpreter.clone()
             };
diff --git a/tests/common/integration.rs b/tests/common/integration.rs
index 85f10b0d1..91a0d6afd 100644
--- a/tests/common/integration.rs
+++ b/tests/common/integration.rs
@@ -74,7 +74,7 @@ pub fn test_integration(
     let interpreter = if build_context.interpreter.is_empty() {
         let error_message = "python3 should be a python interpreter";
         let venv_interpreter = PythonInterpreter::check_executable(
-            "python3",
+            python_interp.as_deref().unwrap_or("python3"),
             &build_context.target,
             &build_context.bridge,
         )
diff --git a/tests/common/mod.rs b/tests/common/mod.rs
index cd85ee4bc..9b2fbb0ed 100644
--- a/tests/common/mod.rs
+++ b/tests/common/mod.rs
@@ -92,13 +92,30 @@ pub fn handle_result<T>(result: Result<T>) -> T {
     }
 }
 
+/// Get Python implementation
+pub fn get_python_implementation(python_interp: &Path) -> Result<String> {
+    let code = "import sys; print(sys.implementation.name, end='')";
+    let output = Command::new(python_interp).arg("-c").arg(code).output()?;
+    let python_impl = String::from_utf8(output.stdout).unwrap();
+    Ok(python_impl)
+}
+
 /// Create virtualenv
 pub fn create_virtualenv(name: &str, python_interp: Option<PathBuf>) -> Result<(PathBuf, PathBuf)> {
+    let interp = python_interp.or_else(|| test_python_path().map(PathBuf::from));
+    let venv_interp = interp.clone().unwrap_or_else(|| {
+        let target = Target::from_target_triple(None).unwrap();
+        target.get_python()
+    });
+    let venv_name = match get_python_implementation(&venv_interp) {
+        Ok(python_impl) => format!("{}-{}", name, python_impl),
+        Err(_) => name.to_string(),
+    };
     let venv_dir = PathBuf::from("test-crates")
         .normalize()?
         .into_path_buf()
         .join("venvs")
-        .join(name);
+        .join(venv_name);
     let target = Target::from_target_triple(None)?;
 
     if venv_dir.is_dir() {
@@ -106,7 +123,6 @@ pub fn create_virtualenv(name: &str, python_interp: Option<PathBuf>) -> Result<(
     }
 
     let mut cmd = Command::new("virtualenv");
-    let interp = python_interp.or_else(|| test_python_path().map(PathBuf::from));
     if let Some(interp) = interp {
         cmd.arg("-p").arg(interp);
     }
diff --git a/tests/run.rs b/tests/run.rs
index a8049df68..df190dcce 100644
--- a/tests/run.rs
+++ b/tests/run.rs
@@ -1,6 +1,11 @@
 //! To speed up the tests, they are tests all collected in a single module
 
-use common::{develop, editable, errors, handle_result, integration, other};
+use common::{
+    develop, editable, errors, get_python_implementation, handle_result, integration, other,
+    test_python_path,
+};
+use maturin::Target;
+use std::path::PathBuf;
 
 mod common;
 
@@ -145,22 +150,11 @@ fn editable_pyo3_ffi_pure() {
 
 #[test]
 fn integration_pyo3_bin() {
-    use common::test_python_path;
-    use maturin::Target;
-    use std::path::PathBuf;
-    use std::process::Command;
-
     let python = test_python_path().map(PathBuf::from).unwrap_or_else(|| {
         let target = Target::from_target_triple(None).unwrap();
         target.get_python()
     });
-    let code = "import sys; print(sys.implementation.name, end='')";
-    let output = Command::new(python)
-        .arg("-c")
-        .arg(code)
-        .output()
-        .expect("Failed to execute python");
-    let python_implementation = String::from_utf8(output.stdout).unwrap();
+    let python_implementation = get_python_implementation(&python).unwrap();
     if python_implementation == "pypy" {
         // PyPy doesn't support the 'auto-initialize' feature of pyo3
         return;
@@ -322,10 +316,20 @@ fn integration_wasm_hello_world() {
         Some("wasm32-wasi"),
     ));
 
+    let python = test_python_path().map(PathBuf::from).unwrap_or_else(|| {
+        let target = Target::from_target_triple(None).unwrap();
+        target.get_python()
+    });
+    let python_implementation = get_python_implementation(&python).unwrap();
+    let venv_name = format!(
+        "integration-wasm-hello-world-py3-wasm32-wasi-{}",
+        python_implementation
+    );
+
     // Make sure we're actually running wasm
     assert!(Path::new("test-crates")
         .join("venvs")
-        .join("integration-wasm-hello-world-py3-wasm32-wasi")
+        .join(venv_name)
         .join(if cfg!(target_os = "windows") {
             "Scripts"
         } else {