diff --git a/docs/source/networks.rst b/docs/source/networks.rst
index cf383d2908..7c22964835 100644
--- a/docs/source/networks.rst
+++ b/docs/source/networks.rst
@@ -134,6 +134,10 @@ Blocks
 .. autoclass:: LocalNetFeatureExtractorBlock
     :members:
 
+`Warp`
+~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+.. autoclass:: Warp
+    :members:
 
 Layers
 ------
diff --git a/monai/networks/blocks/__init__.py b/monai/networks/blocks/__init__.py
index c33feb4e2b..8ac06f8776 100644
--- a/monai/networks/blocks/__init__.py
+++ b/monai/networks/blocks/__init__.py
@@ -27,3 +27,4 @@
     SEResNeXtBottleneck,
 )
 from .upsample import SubpixelUpsample, Subpixelupsample, SubpixelUpSample, Upsample, UpSample
+from .warp import Warp
diff --git a/monai/networks/blocks/warp.py b/monai/networks/blocks/warp.py
new file mode 100644
index 0000000000..56b289e394
--- /dev/null
+++ b/monai/networks/blocks/warp.py
@@ -0,0 +1,103 @@
+from typing import List, Optional, Union
+
+import torch
+from torch import nn
+from torch.nn import functional as F
+
+from monai.config import USE_COMPILED
+from monai.networks.layers import grid_pull
+from monai.utils import GridSampleMode, GridSamplePadMode
+
+
+class Warp(nn.Module):
+    """
+    Warp an image with given DDF.
+    """
+
+    def __init__(
+        self,
+        spatial_dims: int,
+        mode: Optional[Union[GridSampleMode, str]] = GridSampleMode.BILINEAR,
+        padding_mode: Optional[Union[GridSamplePadMode, str]] = GridSamplePadMode.ZEROS,
+    ):
+        """
+        Args:
+            spatial_dims: {2, 3}. number of spatial dimensions
+            mode: {``"bilinear"``, ``"nearest"``}
+                Interpolation mode to calculate output values. Defaults to ``"bilinear"``.
+                See also: https://pytorch.org/docs/stable/nn.functional.html#grid-sample
+            padding_mode: {``"zeros"``, ``"border"``, ``"reflection"``}
+                Padding mode for outside grid values. Defaults to ``"border"``.
+                See also: https://pytorch.org/docs/stable/nn.functional.html#grid-sample
+        """
+        super(Warp, self).__init__()
+        if spatial_dims not in [2, 3]:
+            raise ValueError(f"got unsupported spatial_dims = {spatial_dims}, only support 2-d and 3-d input")
+        self.spatial_dims = spatial_dims
+        self.mode: GridSampleMode = GridSampleMode(mode)
+        self.padding_mode: GridSamplePadMode = GridSamplePadMode(padding_mode)
+
+    @staticmethod
+    def get_reference_grid(ddf: torch.Tensor) -> torch.Tensor:
+        mesh_points = [torch.arange(0, dim) for dim in ddf.shape[2:]]
+        grid = torch.stack(torch.meshgrid(*mesh_points[::-1]), dim=0)  # (spatial_dims, ...)
+        grid = torch.stack([grid] * ddf.shape[0], dim=0)  # (batch, spatial_dims, ...)
+        grid = grid.to(ddf)
+        return grid
+
+    @staticmethod
+    def normalize_grid(grid: torch.Tensor) -> torch.Tensor:
+        # (batch, ..., self.spatial_dims)
+        for i, dim in enumerate(grid.shape[1:-1]):
+            grid[..., i] = grid[..., i] * 2 / (dim - 1) - 1
+        return grid
+
+    def forward(self, image: torch.Tensor, ddf: torch.Tensor) -> torch.Tensor:
+        """
+        Args:
+            image: Tensor in shape (batch, num_channels, H, W[, D])
+            ddf: Tensor in the same spatial size as image, in shape (batch, spatial_dims, H, W[, D])
+
+        Returns:
+            warped_image in the same shape as image (batch, num_channels, H, W[, D])
+        """
+        if len(image.shape) != 2 + self.spatial_dims:
+            raise ValueError(f"expecting {self.spatial_dims + 2}-d input, " f"got input in shape {image.shape}")
+        if len(ddf.shape) != 2 + self.spatial_dims or ddf.shape[1] != self.spatial_dims:
+            raise ValueError(
+                f"expecting {self.spatial_dims + 2}-d ddf with {self.spatial_dims} channels, "
+                f"got ddf in shape {ddf.shape}"
+            )
+        if image.shape[0] != ddf.shape[0] or image.shape[2:] != ddf.shape[2:]:
+            raise ValueError(
+                "expecting image and ddf of same batch size and spatial size, "
+                f"got image of shape {image.shape}, ddf of shape {ddf.shape}"
+            )
+
+        grid = self.get_reference_grid(ddf) + ddf
+        grid = grid.permute([0] + list(range(2, 2 + self.spatial_dims)) + [1])  # (batch, ..., self.spatial_dims)
+
+        if USE_COMPILED:
+            _padding_mode = self.padding_mode.value
+            if _padding_mode == "zeros":
+                bound = 7
+            elif _padding_mode == "border":
+                bound = 0
+            else:
+                bound = 1
+            _interp_mode = self.mode.value
+            warped_image: torch.Tensor = grid_pull(
+                image,
+                grid,
+                bound=bound,
+                extrapolate=True,
+                interpolation=1 if _interp_mode == "bilinear" else _interp_mode,
+            )
+        else:
+            grid = self.normalize_grid(grid)
+            index_ordering: List[int] = list(range(self.spatial_dims - 1, -1, -1))
+            grid = grid[..., index_ordering]  # z, y, x -> x, y, z
+            warped_image = F.grid_sample(
+                image, grid, mode=self.mode.value, padding_mode=self.padding_mode.value, align_corners=True
+            )
+        return warped_image
diff --git a/tests/test_warp.py b/tests/test_warp.py
new file mode 100644
index 0000000000..ba8bc9a994
--- /dev/null
+++ b/tests/test_warp.py
@@ -0,0 +1,96 @@
+import unittest
+
+import numpy as np
+import torch
+from parameterized import parameterized
+
+from monai.networks.blocks.warp import Warp
+
+TEST_CASE = [
+    [
+        {"spatial_dims": 2, "mode": "bilinear", "padding_mode": "zeros"},
+        {"image": torch.arange(4).reshape((1, 1, 2, 2)).to(dtype=torch.float), "ddf": torch.zeros(1, 2, 2, 2)},
+        torch.arange(4).reshape((1, 1, 2, 2)),
+    ],
+    [
+        {"spatial_dims": 2, "mode": "nearest", "padding_mode": "zeros"},
+        {"image": torch.arange(4).reshape((1, 1, 2, 2)).to(dtype=torch.float), "ddf": torch.zeros(1, 2, 4, 4)},
+        torch.tensor([[0.0, 0.0, 0.0, 0.0], [0.0, 0.0, 1.0, 0.0], [0.0, 2.0, 3.0, 0.0], [0.0, 0.0, 0.0, 0.0]])
+        .unsqueeze(0)
+        .unsqueeze(0),
+    ],
+    [
+        {"spatial_dims": 2, "mode": "bilinear", "padding_mode": "border"},
+        {"image": torch.arange(4).reshape((1, 1, 2, 2)).to(dtype=torch.float), "ddf": torch.zeros(1, 2, 4, 4)},
+        torch.tensor([[0.0, 0.0, 1.0, 1.0], [0.0, 0.0, 1.0, 1.0], [2.0, 2.0, 3, 3.0], [2.0, 2.0, 3.0, 3.0]])
+        .unsqueeze(0)
+        .unsqueeze(0),
+    ],
+    [
+        {"spatial_dims": 2, "mode": "nearest", "padding_mode": "reflection"},
+        {"image": torch.arange(4).reshape((1, 1, 2, 2)).to(dtype=torch.float), "ddf": torch.zeros(1, 2, 4, 4)},
+        torch.tensor([[3.0, 2.0, 3.0, 2.0], [1.0, 0.0, 1.0, 0.0], [3.0, 2.0, 3.0, 2.0], [1.0, 0.0, 1.0, 0.0]])
+        .unsqueeze(0)
+        .unsqueeze(0),
+    ],
+    [
+        {"spatial_dims": 3, "mode": "bilinear", "padding_mode": "zeros"},
+        {"image": torch.arange(8).reshape((1, 1, 2, 2, 2)).to(dtype=torch.float), "ddf": torch.zeros(1, 3, 2, 2, 2)},
+        torch.arange(8).reshape((1, 1, 2, 2, 2)).to(dtype=torch.float),
+    ],
+]
+
+TEST_CASES = [
+    [
+        {"spatial_dims": 2, "mode": "bilinear", "padding_mode": "zeros"},
+        {"image": torch.arange(4).reshape((1, 1, 2, 2)).to(dtype=torch.float), "ddf": torch.zeros(1, 2, 2, 2)},
+        torch.arange(4).reshape((1, 1, 2, 2)),
+    ],
+    [
+        {"spatial_dims": 2, "mode": "bilinear", "padding_mode": "zeros"},
+        {"image": torch.arange(4).reshape((1, 1, 2, 2)).to(dtype=torch.float), "ddf": torch.ones(1, 2, 2, 2)},
+        torch.tensor([[[[3, 0], [0, 0]]]]),
+    ],
+    [
+        {"spatial_dims": 3, "mode": "nearest", "padding_mode": "border"},
+        {
+            "image": torch.arange(8).reshape((1, 1, 2, 2, 2)).to(dtype=torch.float),
+            "ddf": torch.ones(1, 3, 2, 2, 2) * -1,
+        },
+        torch.tensor([[[[[0, 0], [0, 0]], [[0, 0], [0, 0]]]]]),
+    ],
+    [
+        {"spatial_dims": 3, "mode": "nearest", "padding_mode": "reflection"},
+        {"image": torch.arange(8).reshape((1, 1, 2, 2, 2)).to(dtype=torch.float), "ddf": torch.ones(1, 3, 2, 2, 2)},
+        torch.tensor([[[[[7, 6], [5, 4]], [[3, 2], [1, 0]]]]]),
+    ],
+]
+
+
+class TestWarp(unittest.TestCase):
+    @parameterized.expand(TEST_CASES)
+    def test_resample(self, input_param, input_data, expected_val):
+        warp_layer = Warp(**input_param)
+        result = warp_layer(**input_data)
+        np.testing.assert_allclose(result.cpu().numpy(), expected_val.cpu().numpy(), rtol=1e-4, atol=1e-4)
+
+    def test_ill_shape(self):
+        warp_layer = Warp(spatial_dims=2)
+        with self.assertRaisesRegex(ValueError, ""):
+            warp_layer(
+                image=torch.arange(4).reshape((1, 1, 1, 2, 2)).to(dtype=torch.float), ddf=torch.zeros(1, 2, 2, 2)
+            )
+        with self.assertRaisesRegex(ValueError, ""):
+            warp_layer(
+                image=torch.arange(4).reshape((1, 1, 2, 2)).to(dtype=torch.float), ddf=torch.zeros(1, 2, 1, 2, 2)
+            )
+        with self.assertRaisesRegex(ValueError, ""):
+            warp_layer(image=torch.arange(4).reshape((1, 1, 2, 2)).to(dtype=torch.float), ddf=torch.zeros(1, 2, 3, 3))
+
+    def test_ill_opts(self):
+        with self.assertRaisesRegex(ValueError, ""):
+            Warp(spatial_dims=4)
+
+
+if __name__ == "__main__":
+    unittest.main()