simulated_BOLD_time_series

Simulated BOLD time series

Task design *.mat file is used as an input for TMFC simulations using Python code.

The output of the Python code is simulated BOLD time series *.mat file.

Task design and simulated BOLD time series *.mat files are used as input for TMFC analysis using MATLAB code.

"Simulated BOLD time series" data structures

• oscill - oscillatory-related BOLD signal, [m x n x o] matrix, where m - time point, n - brain region, o - subject
• coact - coactivation-related BOLD signal, [m x n] matrix, where m - time point, n - brain region

Experiments:

• SIM_BOLD 01_BLOCK [2s_TR] [20s_DUR] [10_BLOCKS]

  • Block design
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 10 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 13.3 min

• SIM_BOLD 01_BLOCK [2s_TR] [20s_DUR] [10_BLOCKS] [NO_TMFC]

  • Block design
  • No task-modulated functional connectivity (synaptic weight matrices are the same for Rest, Cond A and Cond B)
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 10 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 13.3 min

• SIM_BOLD 01_BLOCK [2s_TR] [20s_DUR] [10_BLOCKS] [Variable_HRF]

  • Block design
  • Variable parameters of the Balloon-Windkessel hemodynamic model (time-to-peak = 3-7 s)
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 10 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 13.3 min

• SIM_BOLD 02_EVENT [2s_TR] [1s_DUR] [6s_ISI] [100_TRIALS]

  • Default event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 23.6 min

• SIM_BOLD 02_EVENT [2s_TR] [1s_DUR] [6s_ISI] [100_TRIALS] [Variable_HRF]

  • Default event-related design
  • Variable parameters of the Balloon-Windkessel hemodynamic model (time-to-peak = 3-7 s)
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 23.6 min

• SIM_BOLD 03_EVENT [500ms_TR] [1s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 500 ms
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 14 time points (7 s)
  • Total scan time = 23.6 min

• SIM_BOLD 04_EVENT [700ms_TR] [1s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 700 ms
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 10 time points (7 s)
  • Total scan time = 23.6 min

• SIM_BOLD 05_EVENT [1s_TR] [1s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 1 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 6 time points (6 s)
  • Total scan time = 23.6 min

• SIM_BOLD 06_EVENT [3s_TR] [1s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 3 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (9 s)
  • Total scan time = 23.6 min

• SIM_BOLD 07_EVENT [2s_TR] [100ms_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 100 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 20.6 min

• SIM_BOLD 08_EVENT [2s_TR] [250ms_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 250 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 21.1 min

• SIM_BOLD 09_EVENT [2s_TR] [500ms_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 500 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 22 min

• SIM_BOLD 10_EVENT [2s_TR] [2s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 2 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 27 min

• SIM_BOLD 11_EVENT [2s_TR] [4s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 4 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 33.8 min

• SIM_BOLD 12_EVENT [2s_TR] [1s_DUR] [2s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 1-3 s (mean ISI = 2 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 10.4 min

• SIM_BOLD 13_EVENT [2s_TR] [1s_DUR] [4s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 2-6 s (mean ISI = 4 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 17 min

• SIM_BOLD 14_EVENT [2s_TR] [1s_DUR] [8s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 6-10 s (mean ISI = 8 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 30.4 min

• SIM_BOLD 15_EVENT [2s_TR] [1s_DUR] [12s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 10-14 s (mean ISI = 12 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 44 min

• SIM_BOLD 16_EVENT [2s_TR] [1s_DUR] [6s_ISI] [20_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 20 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 5 min

• SIM_BOLD 17_EVENT [2s_TR] [1s_DUR] [6s_ISI] [40_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 40 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 9.7 min

• SIM_BOLD 18_EVENT [2s_TR] [1s_DUR] [6s_ISI] [60_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 60 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 14 min

• SIM_BOLD 19_EVENT [2s_TR] [1s_DUR] [6s_ISI] [80_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 80 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 19 min

• SIM_BOLD 20_EVENT [2s_TR] [100ms_DUR] [6s_ISI] [200_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 100 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 200 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 40.9 min

• SIM_BOLD 21_EVENT [500ms_TR] [100ms_DUR] [6s_ISI] [50_TRIALS]

  • Event-related design
  • TR = 500 ms
  • Event duration = 100 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 50 events per condition
  • Dummy scans: first 14 time points (7 s)
  • Total scan time = 10.3 min

• SIM_BOLD 22_EVENT [700ms_TR] [100ms_DUR] [6s_ISI] [70_TRIALS]

  • Event-related design
  • TR = 700 ms
  • Event duration = 100 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 70 events per condition
  • Dummy scans: first 10 time points (7 s)
  • Total scan time = 14.4 min

• SIM_BOLD 23_EVENT [1s_TR] [100ms_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 1 s
  • Event duration = 100 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 6 time points (6 s)
  • Total scan time = 20.6 min

• SIM_BOLD 24_BLOCK [2s_TR] [20s_DUR] [10_BLOCKS] [ASYMMETRIC]

  • Block design
  • Asymmetric synaptic weight matrices
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 10 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 13.3 min

• SIM_BOLD 25_BLOCK [2s_TR] [20s_DUR] [20_BLOCKS] [ASYMMETRIC]

  • Block design
  • Asymmetric synaptic weight matrices
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 20 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 26.6 min

• SIM_BOLD 25_BLOCK [2s_TR] [20s_DUR] [20_BLOCKS] [ASYMMETRIC] [Variable_HRF]

  • Block design
  • Asymmetric synaptic weight matrices
  • Variable parameters of the Balloon-Windkessel hemodynamic model (time-to-peak = 3-7 s)
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 20 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 26.6 min

• SIM_BOLD 26_EVENT [2s_TR] [1s_DUR] [6s_ISI] [100_TRIALS] [ASYMMETRIC]

  • Event-related design
  • Asymmetric synaptic weight matrices
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 23.6 min

• SIM_BOLD 27_EVENT [2s_TR] [1s_DUR] [6s_ISI] [200_TRIALS] [ASYMMETRIC]

  • Event-related design
  • Asymmetric synaptic weight matrices
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 200 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 40.9 min

• SIM_BOLD 27_EVENT [2s_TR] [1s_DUR] [6s_ISI] [200_TRIALS] [ASYMMETRIC] [Variable_HRF]

  • Event-related design
  • Asymmetric synaptic weight matrices
  • Variable parameters of the Balloon-Windkessel hemodynamic model (time-to-peak = 3-7 s)
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 200 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 40.9 min

• SIM_BOLD 28_BLOCK [720ms_TR] [HCP_WM]

  • Block design (Human Connectome Project, Working Memory Task)
  • Repetition time (TR) = 720 ms
  • Task block duration = 27.5 s (2-back, 1-back)
  • Rest (R) = 15 s
  • 8 blocks per condition
  • Block sequence: [2-b, 1-b, R, 2-b, 1-b, R, 2-b, 2-b, R, 1-b, 1-b, R, 2-b, 1-b, R, 2-b, 1-b, R, 1-b, 2-b, R, 1-b, 2-b]
  • Dummy scans: first 25 time points (18 s)
  • Total scan time = 10 min

• SIM_BOLD 29_BLOCK [720ms_TR] [HCP_SOCIAL]

  • Block design (Human Connectome Project, Social Cognition Task)
  • Repetition time (TR) = 720 ms
  • Task block duration = 23 s (Social, Random)
  • Rest (R) = 15 s
  • 5 blocks per condition
  • Block sequence: [Soc, R, Soc, R, Rnd, R, Soc, R, Rnd, Soc, R, Rnd, R, Rnd, R, Soc, R, Rnd, R]
  • Dummy scans: first 25 time points (18 s)
  • Total scan time = 7 min

• SIM_BOLD 30_EVENT [2s_TR] [CNP_SST] [All_stop_trials]

  • Event-related design (UCLA Consortium for Neuropsychiatric Phenomics, Stop Signal Task)
  • TR = 2 s
  • Event duration = 1.5 s
  • Random interstimulus interval (ISI) = 0.5-4 s (mean ISI = 1 s)
  • 96 GO trials
  • 32 STOP-signal trials
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 7 min

• SIM_BOLD 31_EVENT [2s_TR] [CNP_SST] [Correct_stop_trials]

  • Unbalanced event-related design (UCLA Consortium for Neuropsychiatric Phenomics, Stop Signal Task)
  • TR = 2 s
  • Event duration = 1.5 s
  • Random interstimulus interval (ISI) = 0.5-4 s (mean ISI = 1 s)
  • 94 GO trials
  • 17 Correct STOP-signal trials
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 7 min

• SIM_BOLD 32_EVENT [2s_TR] [CNP_TST] [Switch_vs_NoSwitch]

  • Unbalanced event-related design (UCLA Consortium for Neuropsychiatric Phenomics, Task Switching Task)
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI), mean ISI = 3 s
  • 24 Switch trials
  • 72 No Switch trials
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 6 min

• SIM_BOLD 33_BLOCK [2s_TR] [20s_DUR] [20_BLOCKS] [Variable_HRF]

  • Block design
  • Variable parameters of the Balloon-Windkessel hemodynamic model (time-to-peak = 3-7 s)
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 20 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 26.6 min