Hessian error while NPAG run #222
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VishnuEriyat
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I was doing an NPAG run for a rifampicin model, the run stopped before attaining convergence and is showing Hessian error. Previously the same model and data file I had used for an NPAG run, which attained convergence. The only change I made in the run which did not converge is that I added a secondary variable block where volume of distribution is given a weightage with the covariate gender. The coefficient was 0.7 for female and 1 for male. What can be the reason for this?
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