diff --git a/Formula/scipy.rb b/Formula/scipy.rb
index 4ff09cedf85e5..a9bc1f3237d99 100644
--- a/Formula/scipy.rb
+++ b/Formula/scipy.rb
@@ -28,6 +28,10 @@ class Scipy < Formula
   cxxstdlib_check :skip
 
   def install
+    # Fix for current GCC on Big Sur, which does not like 11 as version value
+    # (reported at https://github.com/iains/gcc-darwin-arm64/issues/31#issuecomment-750343944)
+    ENV["MACOSX_DEPLOYMENT_TARGET"] = "11.0" if MacOS.version == :big_sur
+
     openblas = Formula["openblas"].opt_prefix
     ENV["ATLAS"] = "None" # avoid linking against Accelerate.framework
     ENV["BLAS"] = ENV["LAPACK"] = "#{openblas}/lib/#{shared_library("libopenblas")}"