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Microbiome GWAS

Created by: Esteban Lopera, Robert Warmerdam
Created on: 25-09-2021.
Contact information: e.a.lopera.maya@umcg.nl.

DESCRIPTION

Here you will find the script used to calculate GWAS for microbiome features in the UMCG high performace computing cluster.

BASIC INPUT (for gwas)

-Genotype files (VCF, BGEN or GDS).
-Phenotype(s) files.
-list of selected SNPs for GRM (GDS or plink format).
-list of covariates (or model).

INSTRUCTIONS

Prepare vcf of bgen files with their respective index files and make sure they have the dosage (DS field).
Detailed instructions are found in the respective folder.