diff --git a/ddtrace/contrib/redis/patch.py b/ddtrace/contrib/redis/patch.py
index da088659b23..eeca1b96fa7 100644
--- a/ddtrace/contrib/redis/patch.py
+++ b/ddtrace/contrib/redis/patch.py
@@ -1,4 +1,5 @@
 import redis
+from six import PY3
 
 from ddtrace import config
 from ddtrace.vendor import wrapt
@@ -36,7 +37,8 @@ def patch():
         _w("redis", "Redis.pipeline", traced_pipeline)
         _w("redis.client", "Pipeline.execute", traced_execute_pipeline)
         _w("redis.client", "Pipeline.immediate_execute_command", traced_execute_command)
-        if redis.VERSION >= (4, 2, 0):
+        # Avoid mypy invalid syntax errors when parsing Python 2 files
+        if PY3 and redis.VERSION >= (4, 2, 0):
             from .asyncio_patch import traced_async_execute_command
             from .asyncio_patch import traced_async_execute_pipeline
 
diff --git a/docs/spelling_wordlist.txt b/docs/spelling_wordlist.txt
index 1de25b828c5..88fe2a50740 100644
--- a/docs/spelling_wordlist.txt
+++ b/docs/spelling_wordlist.txt
@@ -108,6 +108,7 @@ mongoengine
 multiline
 multiprocess
 multithreaded
+mypy
 mysql
 mysqlclient
 mysqldb
diff --git a/releasenotes/notes/fix-mypy-py2-redis-4c8d3b4e461c6074.yaml b/releasenotes/notes/fix-mypy-py2-redis-4c8d3b4e461c6074.yaml
new file mode 100644
index 00000000000..3eb2c42ab4d
--- /dev/null
+++ b/releasenotes/notes/fix-mypy-py2-redis-4c8d3b4e461c6074.yaml
@@ -0,0 +1,4 @@
+---
+fixes:
+  - |
+    mypy: Avoid parsing redis asyncio files when type checking Python 2