diff --git a/integration-tests/appsec/index.spec.js b/integration-tests/appsec/index.spec.js
new file mode 100644
index 00000000000..bd38eb0468d
--- /dev/null
+++ b/integration-tests/appsec/index.spec.js
@@ -0,0 +1,113 @@
+'use strict'
+
+const getPort = require('get-port')
+const { createSandbox, FakeAgent, spawnProc } = require('../helpers')
+const path = require('path')
+const Axios = require('axios')
+const { assert } = require('chai')
+
+describe('RASP', () => {
+  let axios, sandbox, cwd, appPort, appFile, agent, proc, stdioHandler
+
+  function stdOutputHandler (data) {
+    stdioHandler && stdioHandler(data)
+  }
+
+  before(async () => {
+    sandbox = await createSandbox(['express'])
+    appPort = await getPort()
+    cwd = sandbox.folder
+    appFile = path.join(cwd, 'appsec/rasp/index.js')
+    axios = Axios.create({
+      baseURL: `http://localhost:${appPort}`
+    })
+  })
+
+  beforeEach(async () => {
+    agent = await new FakeAgent().start()
+    proc = await spawnProc(appFile, {
+      cwd,
+      env: {
+        AGENT_PORT: agent.port,
+        APP_PORT: appPort,
+        DD_APPSEC_ENABLED: true,
+        DD_APPSEC_RASP_ENABLED: true,
+        DD_APPSEC_RULES: path.join(cwd, 'appsec/rasp/rasp_rules.json')
+      }
+    }, stdOutputHandler, stdOutputHandler)
+  })
+
+  afterEach(async () => {
+    proc.kill()
+    await agent.stop()
+  })
+
+  after(async () => {
+    await sandbox.remove()
+  })
+
+  async function testNotCrashedAfterBlocking (path) {
+    let hasOutput = false
+    stdioHandler = () => {
+      hasOutput = true
+    }
+    try {
+      await axios.get(`${path}?host=ifconfig.pro`)
+      assert.fail('Request should have failed')
+    } catch (e) {
+      if (!e.response) {
+        throw e
+      }
+      assert.strictEqual(e.response.status, 403)
+    }
+    return new Promise((resolve, reject) => {
+      setTimeout(() => {
+        if (hasOutput) {
+          reject(new Error('Unexpected output in stdout/stderr after blocking request'))
+        } else {
+          resolve()
+        }
+      }, 50)
+    })
+  }
+
+  describe('ssrf', () => {
+    it('should block when error is unhandled', async () => {
+      try {
+        await axios.get('/ssrf/http/unhandled-error?host=ifconfig.pro')
+        assert.fail('Request should have failed')
+      } catch (e) {
+        assert.strictEqual(e.response.status, 403)
+      }
+    })
+
+    // Not implemented yet
+    it('should not crash the app when app send data after blocking', () => {
+      return testNotCrashedAfterBlocking('/ssrf/http/unhandled-async-write-A')
+    })
+
+    it('should not crash the app when app stream data after blocking', () => {
+      return testNotCrashedAfterBlocking('/ssrf/http/unhandled-async-write-B')
+    })
+
+    it('should not crash the app when setHeader, writeHead or end after blocking', () => {
+      return testNotCrashedAfterBlocking('/ssrf/http/unhandled-async-write-C')
+    })
+
+    it('should not crash the app when appendHeader, flushHeaders, removeHeader after blocking', () => {
+      return testNotCrashedAfterBlocking('/ssrf/http/unhandled-async-write-D')
+    })
+
+    it('should not crash the app when writeContinue after blocking', () => {
+      return testNotCrashedAfterBlocking('/ssrf/http/unhandled-async-write-E')
+    })
+
+    it('should not crash the app when writeProcessing after blocking', () => {
+      return testNotCrashedAfterBlocking('/ssrf/http/unhandled-async-write-F')
+    })
+
+    it('should not crash the app when writeEarlyHints after blocking', () => {
+      return testNotCrashedAfterBlocking('/ssrf/http/unhandled-async-write-G')
+    })
+  })
+})
diff --git a/integration-tests/appsec/rasp/index.js b/integration-tests/appsec/rasp/index.js
new file mode 100644
index 00000000000..e2912a08688
--- /dev/null
+++ b/integration-tests/appsec/rasp/index.js
@@ -0,0 +1,97 @@
+'use strict'
+
+const path = require('path')
+const fs = require('fs')
+require('dd-trace').init()
+
+const http = require('https')
+const express = require('express')
+
+const app = express()
+const port = process.env.APP_PORT || 3000
+
+app.get('/ping', (req, res) => {
+  res.end('pong')
+})
+
+function makeOutgoingRequestAndCbAfterTimeout (req, res, cb) {
+  let finished = false
+  setTimeout(() => {
+    if (!finished && cb) {
+      cb()
+    }
+  }, 10)
+
+  http.get(`https://${req.query.host}`, () => {
+    finished = true
+    res.send('end')
+  })
+}
+
+app.get('/ssrf/http/unhandled-error', (req, res) => {
+  makeOutgoingRequestAndCbAfterTimeout(req, res)
+})
+app.get('/ssrf/http/unhandled-async-write-A', (req, res) => {
+  makeOutgoingRequestAndCbAfterTimeout(req, res, () => {
+    res.send('Late end')
+  })
+})
+
+app.get('/ssrf/http/unhandled-async-write-B', (req, res) => {
+  makeOutgoingRequestAndCbAfterTimeout(req, res, () => {
+    streamFile(res)
+  })
+})
+
+app.get('/ssrf/http/unhandled-async-write-C', (req, res) => {
+  makeOutgoingRequestAndCbAfterTimeout(req, res, () => {
+    res.setHeader('key', 'value')
+    res.writeHead(200, 'OK', ['key2', 'value2'])
+    res.write('test\n')
+    res.end('end')
+  })
+})
+
+app.get('/ssrf/http/unhandled-async-write-D', (req, res) => {
+  makeOutgoingRequestAndCbAfterTimeout(req, res, () => {
+    res.setHeader('key', 'value')
+    res.appendHeader('key2', 'value2')
+    res.removeHeader('key')
+    res.flushHeaders()
+    res.end('end')
+  })
+})
+
+app.get('/ssrf/http/unhandled-async-write-E', (req, res) => {
+  makeOutgoingRequestAndCbAfterTimeout(req, res, () => {
+    res.writeContinue()
+    res.end()
+  })
+})
+
+app.get('/ssrf/http/unhandled-async-write-F', (req, res) => {
+  makeOutgoingRequestAndCbAfterTimeout(req, res, () => {
+    res.writeProcessing()
+    res.end()
+  })
+})
+
+app.get('/ssrf/http/unhandled-async-write-G', (req, res) => {
+  makeOutgoingRequestAndCbAfterTimeout(req, res, () => {
+    const earlyHintsLink = '</styles.css>; rel=preload; as=style'
+    res.writeEarlyHints({
+      link: earlyHintsLink
+    })
+    res.end()
+  })
+})
+
+function streamFile (res) {
+  const stream = fs.createReadStream(path.join(__dirname, 'streamtest.txt'), { encoding: 'utf8' })
+  stream.pipe(res, { end: false })
+  stream.on('end', () => res.end('end'))
+}
+
+app.listen(port, () => {
+  process.send({ port })
+})
diff --git a/integration-tests/appsec/rasp/rasp_rules.json b/integration-tests/appsec/rasp/rasp_rules.json
new file mode 100644
index 00000000000..6e6913b0311
--- /dev/null
+++ b/integration-tests/appsec/rasp/rasp_rules.json
@@ -0,0 +1,59 @@
+{
+  "version": "2.2",
+  "metadata": {
+    "rules_version": "1.99.0"
+  },
+  "rules": [
+    {
+      "id": "test-rule-id-2",
+      "name": "Server-side request forgery exploit",
+      "enabled": true,
+      "tags": {
+        "type": "ssrf",
+        "category": "vulnerability_trigger",
+        "cwe": "918",
+        "capec": "1000/225/115/664",
+        "confidence": "0",
+        "module": "rasp"
+      },
+      "conditions": [
+        {
+          "parameters": {
+            "resource": [
+              {
+                "address": "server.io.net.url"
+              }
+            ],
+            "params": [
+              {
+                "address": "server.request.query"
+              },
+              {
+                "address": "server.request.body"
+              },
+              {
+                "address": "server.request.path_params"
+              },
+              {
+                "address": "grpc.server.request.message"
+              },
+              {
+                "address": "graphql.server.all_resolvers"
+              },
+              {
+                "address": "graphql.server.resolver"
+              }
+            ]
+          },
+          "operator": "ssrf_detector"
+        }
+      ],
+      "transformers": [],
+      "on_match": [
+        "block",
+        "stack_trace"
+      ]
+    }
+  ]
+}
+
diff --git a/integration-tests/appsec/rasp/streamtest.txt b/integration-tests/appsec/rasp/streamtest.txt
new file mode 100644
index 00000000000..9daeafb9864
--- /dev/null
+++ b/integration-tests/appsec/rasp/streamtest.txt
@@ -0,0 +1 @@
+test
diff --git a/integration-tests/helpers.js b/integration-tests/helpers.js
index b8972540e1f..9fdb01cbf9d 100644
--- a/integration-tests/helpers.js
+++ b/integration-tests/helpers.js
@@ -162,7 +162,7 @@ class FakeAgent extends EventEmitter {
   }
 }
 
-function spawnProc (filename, options = {}, stdioHandler) {
+function spawnProc (filename, options = {}, stdioHandler, stderrHandler) {
   const proc = fork(filename, { ...options, stdio: 'pipe' })
   return new Promise((resolve, reject) => {
     proc
@@ -187,6 +187,9 @@ function spawnProc (filename, options = {}, stdioHandler) {
     })
 
     proc.stderr.on('data', data => {
+      if (stderrHandler) {
+        stderrHandler(data)
+      }
       // eslint-disable-next-line no-console
       if (!options.silent) console.error(data.toString())
     })
diff --git a/packages/dd-trace/src/appsec/blocking.js b/packages/dd-trace/src/appsec/blocking.js
index f3d2103b59e..6c14a44c63c 100644
--- a/packages/dd-trace/src/appsec/blocking.js
+++ b/packages/dd-trace/src/appsec/blocking.js
@@ -118,6 +118,8 @@ function block (req, res, rootSpan, abortController, actionParameters) {
   res.writeHead(statusCode, headers).end(body)
 
   abortController?.abort()
+
+  // TODO add res in blocked weak set when response blocking is merged
 }
 
 function getBlockingAction (actions) {
diff --git a/packages/dd-trace/src/appsec/rasp.js b/packages/dd-trace/src/appsec/rasp.js
index 268a0a5bd82..940f0aec1ad 100644
--- a/packages/dd-trace/src/appsec/rasp.js
+++ b/packages/dd-trace/src/appsec/rasp.js
@@ -3,7 +3,28 @@
 const { storage } = require('../../../datadog-core')
 const addresses = require('./addresses')
 const { httpClientRequestStart } = require('./channels')
+const web = require('../plugins/util/web')
 const waf = require('./waf')
+const { getBlockingAction, block } = require('./blocking')
+
+class AbortError extends Error {
+  constructor (req, res, blockingAction) {
+    super('AbortError')
+    this.name = 'AbortError'
+    this.req = req
+    this.res = res
+    this.blockingAction = blockingAction
+  }
+}
+
+function handleUncaughtException (err) {
+  if (err instanceof AbortError) {
+    const { req, res, blockingAction } = err
+    block(req, res, web.root(req), null, blockingAction)
+  } else {
+    throw err
+  }
+}
 
 const RULE_TYPES = {
   SSRF: 'ssrf'
@@ -11,10 +32,14 @@ const RULE_TYPES = {
 
 function enable () {
   httpClientRequestStart.subscribe(analyzeSsrf)
+
+  process.on('uncaughtException', handleUncaughtException)
 }
 
 function disable () {
   if (httpClientRequestStart.hasSubscribers) httpClientRequestStart.unsubscribe(analyzeSsrf)
+
+  process.off('uncaughtException', handleUncaughtException)
 }
 
 function analyzeSsrf (ctx) {
@@ -27,10 +52,20 @@ function analyzeSsrf (ctx) {
   const persistent = {
     [addresses.HTTP_OUTGOING_URL]: url
   }
-  // TODO: Currently this is only monitoring, we should
-  //     block the request if SSRF attempt and
-  //     generate stack traces
-  waf.run({ persistent }, req, RULE_TYPES.SSRF)
+  // TODO: Currently this is monitoring/blocking, we should
+  //     generate stack traces if SSRF attempts
+  const actions = waf.run({ persistent }, req, RULE_TYPES.SSRF)
+
+  const res = store?.res
+  handleWafResults(actions, ctx.abortData, req, res)
+}
+
+function handleWafResults (actions, abortData, req, res) {
+  const blockingAction = getBlockingAction(actions)
+  if (blockingAction && abortData) {
+    abortData.abortController.abort()
+    abortData.error = new AbortError(req, res, blockingAction)
+  }
 }
 
 module.exports = {
diff --git a/packages/dd-trace/test/appsec/rasp.express.plugin.spec.js b/packages/dd-trace/test/appsec/rasp.express.plugin.spec.js
index 23960db1aa3..b588f2b8916 100644
--- a/packages/dd-trace/test/appsec/rasp.express.plugin.spec.js
+++ b/packages/dd-trace/test/appsec/rasp.express.plugin.spec.js
@@ -61,6 +61,26 @@ withVersions('express', 'express', expressVersion => {
     }
 
     describe('ssrf', () => {
+      async function testBlockingRequest () {
+        try {
+          await axios.get('/?host=ifconfig.pro')
+          assert.fail('Request should be blocked')
+        } catch (e) {
+          if (!e.response) {
+            throw e
+          }
+        }
+
+        await agent.use((traces) => {
+          const span = getWebSpan(traces)
+          assert.property(span.meta, '_dd.appsec.json')
+          assert(span.meta['_dd.appsec.json'].includes('rasp-ssrf-rule-id-1'))
+          assert.equal(span.metrics['_dd.appsec.rasp.rule.eval'], 1)
+          assert(span.metrics['_dd.appsec.rasp.duration'] > 0)
+          assert(span.metrics['_dd.appsec.rasp.duration_ext'] > 0)
+        })
+      }
+
       ['http', 'https'].forEach(protocol => {
         describe(`Test using ${protocol}`, () => {
           it('Should not detect threat', async () => {
@@ -79,20 +99,16 @@ withVersions('express', 'express', expressVersion => {
 
           it('Should detect threat doing a GET request', async () => {
             app = (req, res) => {
-              require(protocol).get(`${protocol}://${req.query.host}`)
-              res.end('end')
+              const clientRequest = require(protocol).get(`${protocol}://${req.query.host}`)
+              clientRequest.on('error', (e) => {
+                if (e.message === 'AbortError') {
+                  res.writeHead(500)
+                }
+                res.end('end')
+              })
             }
 
-            axios.get('/?host=ifconfig.pro')
-
-            await agent.use((traces) => {
-              const span = getWebSpan(traces)
-              assert.property(span.meta, '_dd.appsec.json')
-              assert(span.meta['_dd.appsec.json'].includes('rasp-ssrf-rule-id-1'))
-              assert.equal(span.metrics['_dd.appsec.rasp.rule.eval'], 1)
-              assert(span.metrics['_dd.appsec.rasp.duration'] > 0)
-              assert(span.metrics['_dd.appsec.rasp.duration_ext'] > 0)
-            })
+            await testBlockingRequest()
           })
 
           it('Should detect threat doing a POST request', async () => {
@@ -101,19 +117,15 @@ withVersions('express', 'express', expressVersion => {
                 .request(`${protocol}://${req.query.host}`, { method: 'POST' })
               clientRequest.write('dummy_post_data')
               clientRequest.end()
-              res.end('end')
+              clientRequest.on('error', (e) => {
+                if (e.message === 'AbortError') {
+                  res.writeHead(500)
+                }
+                res.end('end')
+              })
             }
 
-            axios.get('/?host=ifconfig.pro')
-
-            await agent.use((traces) => {
-              const span = getWebSpan(traces)
-              assert.property(span.meta, '_dd.appsec.json')
-              assert(span.meta['_dd.appsec.json'].includes('rasp-ssrf-rule-id-1'))
-              assert.equal(span.metrics['_dd.appsec.rasp.rule.eval'], 1)
-              assert(span.metrics['_dd.appsec.rasp.duration'] > 0)
-              assert(span.metrics['_dd.appsec.rasp.duration_ext'] > 0)
-            })
+            await testBlockingRequest()
           })
         })
       })