diff --git a/doc/api/smartsim_api.rst b/doc/api/smartsim_api.rst
index 2af7295df..045c06b1b 100644
--- a/doc/api/smartsim_api.rst
+++ b/doc/api/smartsim_api.rst
@@ -111,6 +111,7 @@ steps to a batch.
 .. autosummary::
 
     SrunSettings.set_nodes
+    SrunSettings.set_node_feature
     SrunSettings.set_tasks
     SrunSettings.set_tasks_per_node
     SrunSettings.set_walltime
diff --git a/doc/changelog.rst b/doc/changelog.rst
index 18c8f7bb8..9c78bf67c 100644
--- a/doc/changelog.rst
+++ b/doc/changelog.rst
@@ -18,7 +18,8 @@ To be released at some future point in time
 
 Description
 
-- Colo Orchestrator setup now blocks application start until setup finished.
+- Add method to specify node features for a Slurm job
+- Colo Orchestrator setup now blocks application start until setup finished
 - ExecArgs handling correction
 - ReadTheDocs config file added and enabled on PRs
 - Enforce changelog updates
@@ -31,6 +32,9 @@ Description
 
 Detailed Notes
 
+- Users can now specify node features for a Slurm job through
+  ``SrunSettings.set_node_feature``. The method accepts a string
+  or list of strings. (SmartSim-PR529_)
 - The request to the colocated entrypoints file within the shell script
   is now a blocking process. Once the Orchestrator is setup, it returns
   which moves the process to the background and allows the application to
@@ -61,6 +65,7 @@ Detailed Notes
   Slurm and Open MPI. (SmartSim-PR520_)
 
 
+.. _SmartSim-PR529: https://github.com/CrayLabs/SmartSim/pull/529
 .. _SmartSim-PR522: https://github.com/CrayLabs/SmartSim/pull/522
 .. _SmartSim-PR524: https://github.com/CrayLabs/SmartSim/pull/524
 .. _SmartSim-PR520: https://github.com/CrayLabs/SmartSim/pull/520
diff --git a/smartsim/settings/base.py b/smartsim/settings/base.py
index d7760decc..4e5b5cf4e 100644
--- a/smartsim/settings/base.py
+++ b/smartsim/settings/base.py
@@ -325,6 +325,19 @@ def set_time(self, hours: int = 0, minutes: int = 0, seconds: int = 0) -> None:
             self._fmt_walltime(int(hours), int(minutes), int(seconds))
         )
 
+    def set_node_feature(self, feature_list: t.Union[str, t.List[str]]) -> None:
+        """Specify the node feature for this job
+
+        :param feature_list: node feature to launch on
+        :type feature_list: str | list[str]
+        """
+        logger.warning(
+            (
+                "Feature specification not implemented for this "
+                f"RunSettings type: {type(self)}"
+            )
+        )
+
     @staticmethod
     def _fmt_walltime(hours: int, minutes: int, seconds: int) -> str:
         """Convert hours, minutes, and seconds into valid walltime format
diff --git a/smartsim/settings/slurmSettings.py b/smartsim/settings/slurmSettings.py
index 935a8df39..61a3e9841 100644
--- a/smartsim/settings/slurmSettings.py
+++ b/smartsim/settings/slurmSettings.py
@@ -243,6 +243,21 @@ def set_broadcast(self, dest_path: t.Optional[str] = None) -> None:
         """
         self.run_args["bcast"] = dest_path
 
+    def set_node_feature(self, feature_list: t.Union[str, t.List[str]]) -> None:
+        """Specify the node feature for this job
+
+        This sets ``-C``
+
+        :param feature_list: node feature to launch on
+        :type feature_list: str | list[str]
+        :raises TypeError: if not str or list of str
+        """
+        if isinstance(feature_list, str):
+            feature_list = [feature_list.strip()]
+        elif not all(isinstance(feature, str) for feature in feature_list):
+            raise TypeError("node_feature argument must be string or list of strings")
+        self.run_args["C"] = ",".join(feature_list)
+
     @staticmethod
     def _fmt_walltime(hours: int, minutes: int, seconds: int) -> str:
         """Convert hours, minutes, and seconds into valid walltime format
diff --git a/tests/test_run_settings.py b/tests/test_run_settings.py
index 25566248d..056dad64b 100644
--- a/tests/test_run_settings.py
+++ b/tests/test_run_settings.py
@@ -339,6 +339,7 @@ def test_set_format_args(set_str, val, key):
         pytest.param("set_task_map", (3,), id="set_task_map"),
         pytest.param("set_cpus_per_task", (4,), id="set_cpus_per_task"),
         pytest.param("set_hostlist", ("hostlist",), id="set_hostlist"),
+        pytest.param("set_node_feature", ("P100",), id="set_node_feature"),
         pytest.param(
             "set_hostlist_from_file", ("~/hostfile",), id="set_hostlist_from_file"
         ),
diff --git a/tests/test_slurm_settings.py b/tests/test_slurm_settings.py
index aa5b2be11..51d4022dc 100644
--- a/tests/test_slurm_settings.py
+++ b/tests/test_slurm_settings.py
@@ -338,6 +338,21 @@ def test_set_hostlist():
         rs.set_hostlist([5])
 
 
+def test_set_node_feature():
+    rs = SrunSettings("python")
+    rs.set_node_feature(["P100", "V100"])
+    assert rs.run_args["C"] == "P100,V100"
+
+    rs.set_node_feature("P100")
+    assert rs.run_args["C"] == "P100"
+
+    with pytest.raises(TypeError):
+        rs.set_node_feature(5)
+
+    with pytest.raises(TypeError):
+        rs.set_node_feature(["P100", 5])
+
+
 def test_set_hostlist_from_file():
     rs = SrunSettings("python")
     rs.set_hostlist_from_file("./path/to/hostfile")