diff --git a/Cargo.lock b/Cargo.lock
index a74cdc88..c67fde7a 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -887,6 +887,12 @@ dependencies = [
  "spki",
 ]
 
+[[package]]
+name = "portable-atomic"
+version = "1.9.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "cc9c68a3f6da06753e9335d63e27f6b9754dd1920d941135b7ea8224f141adb2"
+
 [[package]]
 name = "ppv-lite86"
 version = "0.2.17"
@@ -932,16 +938,17 @@ dependencies = [
 
 [[package]]
 name = "pyo3"
-version = "0.20.2"
+version = "0.21.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "9a89dc7a5850d0e983be1ec2a463a171d20990487c3cfcd68b5363f1ee3d6fe0"
+checksum = "a5e00b96a521718e08e03b1a622f01c8a8deb50719335de3f60b3b3950f069d8"
 dependencies = [
  "cfg-if",
  "indoc 2.0.4",
  "libc",
  "memoffset",
  "parking_lot",
- "pyo3-build-config 0.20.2",
+ "portable-atomic",
+ "pyo3-build-config 0.21.2",
  "pyo3-ffi",
  "pyo3-macros",
  "unindent",
@@ -958,9 +965,9 @@ dependencies = [
 
 [[package]]
 name = "pyo3-build-config"
-version = "0.20.2"
+version = "0.21.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "07426f0d8fe5a601f26293f300afd1a7b1ed5e78b2a705870c5f30893c5163be"
+checksum = "7883df5835fafdad87c0d888b266c8ec0f4c9ca48a5bed6bbb592e8dedee1b50"
 dependencies = [
  "once_cell",
  "target-lexicon",
@@ -968,19 +975,19 @@ dependencies = [
 
 [[package]]
 name = "pyo3-ffi"
-version = "0.20.2"
+version = "0.21.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "dbb7dec17e17766b46bca4f1a4215a85006b4c2ecde122076c562dd058da6cf1"
+checksum = "01be5843dc60b916ab4dad1dca6d20b9b4e6ddc8e15f50c47fe6d85f1fb97403"
 dependencies = [
  "libc",
- "pyo3-build-config 0.20.2",
+ "pyo3-build-config 0.21.2",
 ]
 
 [[package]]
 name = "pyo3-macros"
-version = "0.20.2"
+version = "0.21.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "05f738b4e40d50b5711957f142878cfa0f28e054aa0ebdfc3fd137a843f74ed3"
+checksum = "77b34069fc0682e11b31dbd10321cbf94808394c56fd996796ce45217dfac53c"
 dependencies = [
  "proc-macro2 1.0.66",
  "pyo3-macros-backend",
@@ -990,12 +997,13 @@ dependencies = [
 
 [[package]]
 name = "pyo3-macros-backend"
-version = "0.20.2"
+version = "0.21.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "0fc910d4851847827daf9d6cdd4a823fbdaab5b8818325c5e97a86da79e8881f"
+checksum = "08260721f32db5e1a5beae69a55553f56b99bd0e1c3e6e0a5e8851a9d0f5a85c"
 dependencies = [
  "heck",
  "proc-macro2 1.0.66",
+ "pyo3-build-config 0.21.2",
  "quote 1.0.32",
  "syn 2.0.32",
 ]
diff --git a/Cargo.toml b/Cargo.toml
index 3a391fab..b372fdea 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -42,7 +42,7 @@ rand_chacha = { version = "0.3.1", optional = true }
 lfsr = { version = "0.3.0", optional = true }
 
 [dependencies.pyo3]
-version = "0.20.2"
+version = "0.21.2"
 features = ["abi3-py38", "extension-module"]
 optional = true