diff --git a/CHANGELOG.md b/CHANGELOG.md
index 2f5a64e..0ccba63 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,7 @@
 ## RENEE development version
 
+- Increase memory for `fastq_screen`. (#188, @kelly-sovacool)
+
 ## RENEE 2.6.4
 
 - Fix spelling of shared SIF directory on biowulf -- it is `/data/CCBR_Pipeliner/SIFs` with a lowercase "s" at the end. (#182, @kelly-sovacool)
diff --git a/config/cluster.json b/config/cluster.json
index 6414cb9..a22a481 100644
--- a/config/cluster.json
+++ b/config/cluster.json
@@ -23,7 +23,8 @@
     },
     "fastq_screen": {
         "threads": "32",
-        "time": "2-00:00:00"
+        "time": "2-00:00:00",
+        "mem": "12g"
     },
     "kraken_pe": {
         "cpus-per-task": "32",